Faculty Member

Teléfono: +34 876 555478

Email: minchole@unizar.es

Address: Campus Río Ebro, Edificio I+D, Lab 6.1.08, C/ Mariano Esquillor, s/n – 50018 Zaragoza (Spain)

ABOUT ME

Ana Mincholé graduated in Physics from the University of Zaragoza, Spain in 2002. She also obtained an MSc with distinction at Chalmers University of Technology, Gothenburg, Sweden, in the MSc program “Nanoscale Physics and Engineering”. She then started a PhD in Biomedical Engineering at the Communication Technology Group at the University of Zaragoza, Spain supervised by Prof. Pablo Laguna. Her PhD focused on the analysis of the electrocardiographic signal and the development of novel ECG biomarkers for the stratification of arrhythmic risk. During her PhD, she conducted research visits to the Laboratory for Biomedical Computer Systems and Imaging at the University of Ljubljana, Slovenia, with Prof. Franc Jager, and to the Argentinian Institute of Mathematics, CONICET with Dr Pedro Arini and Dr Marcelo Risk. After her PhD and a short postdoc experience in the European preDiCt project at the University of Oxford, she was awarded a Marie Curie Intra-European Fellowship for Career Development and joined Prof. Blanca Rodriguez’ group at the Department of Computer Science at the University of Oxford, UK. After the fellowship, she continued working at the University of Oxford holding the position of Senior Research Associate until 2019. Then, she moved to the University of Zaragoza to join the Multiscale in Mechanical and Biological Engineering group within the European PRIMAGE project where she applied her expertise in multiscale modelling and simulation and high-performance computing to model tumour growth.  In 2020, she was awarded a Ramón y Cajal Senior Research Fellowship from the Spanish Ministry of Science and Innovation and joined the Biomedical Signal Interpretation and Computational Simulation (BSICoS) group at the University of Zaragoza in 2021. 

Her research interests include the development and evaluation of synergistic data-driven approaches where modelling and simulation are used to integrate biomedical data at different scales in the investigation of cardiac pathological conditions. This is in line with her expertise in the combination of computational modelling and simulation of physiological processesbiomedical signal analysis and machine learning techniques to stratify risk either drug-induced or due to pathological conditions.

PUBLICATIONS
53 registros « 1 de 2 »

2024

Conferencias

Bueno-Palomeque, F L; Zacur, E; Pueyo, E; Crispi, F; Laguna, P; Mincholé, A

Implications of IUGR-Related Geometric Heart Changes on the ECG and Electrophysiology: an In silico Perspective Conferencia

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

BibTeX

Romagnoli, S; Roquero, A I; Martín-Yebra, A; Palmieri, F; Fernandez-Font, J D; Pueyo, E; Gomis, P; Laguna, P; Lainez, E Arbelo; Mincholé, A

Quantification of Delayed Activation in Right Ventricular Outflow Tract in Brugada Patients Conferencia

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

BibTeX

Madrid, J N; Young, W; van Duijvenboden, S; Munroe, P; Mincholé, A; Ramírez, J

ECG Based Unsupervised Clustering Model Predicts Heart Failure and Cardiovascular Diseases in Individuals without Cardiovascular Disease Conferencia

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

BibTeX

Kayyali, M; Mincholé, A; Qian, S; Young, A; Ugurlu, D; Fairweather, E; Niederer, S; Whitaker, J; Bishop, M; Lamata, P

Cardiac Anatomical and Electrical Axes: Proposed Definitions and Interplay Conferencia

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

BibTeX

2023

Artículos de revista

Bueno-Palomeque, F L; Mountris, K A; Ortigosa, N; Bailón, R; Bijnens, B; Crispi, F; Pueyo, E; Mincholé, A; Laguna, P

QRS-T angles as markers for heart sphericity in subjects with intrauterine growth restriction: a simulation study Artículo de revista

En: IEEE Journal of Biomedical and Health Informatics, vol. 27, no 10, pp. 4707-4718, 2023.

Enlaces | BibTeX

Conferencias

Sales-Bellés, C; Melero, J; Ramos, J; Mincholé, A; Pueyo, E

Análisis frecuencial del complejo QRS del electrocardiograma para la caracterización de la estimulación con marcapasos Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Madrid, J; Ramírez, J; Mincholé, A

ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Noguero-Soler, I; Revilla, P; Ramos, J; Pueyo, E; Mincholé, A

ECG Morphology-Based Markers for Risk Stratification in Hypertrophic Cardiomyopathy Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Rodríguez-Carbó, J; Mincholé, A; Pueyo, E

ECG-based Characterization of the Extent, Severity and Spatial Location of Acute Ischemia in Patients with and without Prior Myocardial Infarction Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Madrid, J; Munroe, P; Duijvenboden, S; Ramírez, J; Mincholé, A

ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Sales-Bellés, C; Mincholé, A; Melero, J; Cabrera-Ramos, M; Montilla-Padilla, I; Sorinas, L; Julián, I; Pueyo, E; Ramos, J

Left Bundle Branch Area Pacing Generates More Physiological Ventricular Activation Sequences than Right Ventricular Pacing Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Bueno-Palomeque, F L; Mountris, K; Ortigosa, N; Bailón, R; Bijnens, B; Crispi, F; Pueyo, E; Mincholé, A; Laguna, P

QRS Width and T-peak to T-end Interval Are Prolonged in Preadolescents with Severe Intrauterine Growth Restriction at Birth When Compared to Controls Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

2022

Conferencias

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Assessment and optimization of conduction system pacing for anti-bradycardia pacemaker therapy Conferencia

STAFF-MALT Symposium 2022, Senohraby, Czech Republic, 2022.

BibTeX

Sales, C; Melero, J; Julián, I; Ramos, J; Mincholé, A; Pueyo, E

Comparación de los efectos de la estimulación cardíaca convencional y la estimulación de rama izquierda sobre la despolarización y repolarización ventricular en el ECG Conferencia

Jornadas de Jóvenes Investigadores del I3A, Zaragoza, España, 2022.

Enlaces | BibTeX

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

2020

Conferencias

Bueno-Palomeque, F L; Mountris, K A; Minchole, A; Ortigosa, N; Pueyo, E; Laguna, P

Changes in QRS and T-wave Loops Subsequent to an Increase in Left Ventricle Globularity as in Intrauterine Growth Restriction: a Simulation Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

2018

Artículos de revista

Lyon, A; Ariga, R; Mincholé, A; Mahmod, M; Ormondroyd, E; Laguna, P; Freitas, N; Neubauer, S; Watkins, H; Rodriguez, B

Distinct ECG phenotypes identified in hypertrophic cardiomyopathy using machine learning associate with arrhythmic risk markers Artículo de revista

En: Frontiers in Physiology, vol. 9, no 213, pp. 1-13, 2018.

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Lyon, A; Mincholé, A; Martínez, J P; Laguna, P; Rodriguez, B

Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances Artículo de revista

En: Journal of the Royal Society: Interface, vol. 15, 2018.

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2017

Artículos de revista

Ramírez, J; Orini, M; Mincholé, A; Monasterio, V; Cygankiewicz, I; Luna, Bayés A; Martínez, J P; Laguna, P; Pueyo, E

Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model Artículo de revista

En: PLOS ONE, vol. 12, no 10: e0186152, pp. 1-15, 2017.

Enlaces | BibTeX

Ramírez, J; Orini, M; Mincholé, A; Monasterio, V; Cygankiewicz, I; Luna, Bayés A; Martínez, J P; Pueyo, E; Laguna, P

T-wave Morphology Restitution Predicts Sudden Cardiac Death in Patients with Chronic Heart Failure Artículo de revista

En: Journal of the American Heart Association, no 6: e005310, pp. 1-12, 2017.

Enlaces | BibTeX

Conferencias

Lyon, A; Ariga, R; Mincholé, A; Zacur, E; Laguna, P; Grau, V; Neubauer, S; Watkins, H; Rodriguez, B

Risk stratification in hypertrophic cardiomyopathy using ECG-based clustering and personalized computer simulations Conferencia

Proceedings of the EMBEC 2017, NBC 2017, 2017.

Enlaces | BibTeX

2015

Artículos de revista

Mincholé, A; Bueno-Orovio, A; Laguna, P; Pueyo, E; Rodriguez, B

ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk Artículo de revista

En: Journal of Electrocardiology, vol. 48, pp. 867-873, 2015.

Enlaces | BibTeX

Ramírez, J; Monasterio, V; Mincholé, A; Llamedo, M; Lenis, G; Cygankiewicz, I; Luna, Bayés A; Malik, M; Martínez, J P; Laguna, P; Pueyo, E

Automatic SVM classification of Sudden Cardiac Death and Pump Failure Death from Autonomic and Repolarization ECG Markers Artículo de revista

En: Journal of Electrocardiology, vol. 48, pp. 551-557, 2015.

Enlaces | BibTeX

Conferencias

Lyon, A; Mincholé, A; Ariga, R; Laguna, P; Neubauer, S; Watkins, H; Freitas, N; Rodríguez, B

Extraction of Morphological QRS-based Biomarkers in Hypertrophic Cardiomyopathy for Risk Stratification using L1 Regularized Logistic Regression Conferencia

XLII International Conference on Computing in Cardiology, Nice, France, 2015.

Enlaces | BibTeX

2014

Artículos de revista

Mincholé, A; Sörnmo, L; Laguna, P

Detection of Body Position Changes from the ECG using a Laplacian Noise Model Artículo de revista

En: Biomedical Signal Processing and Control, vol. 14, pp. 189-196, 2014.

Enlaces | BibTeX

Mincholé, A; Zacur, E; Pueyo, E; Laguna, P

Modeling and Quantification of Repolarization Feature Dependency on Heart Rate Artículo de revista

En: Selected paper for the Special 2013 issue of methods of information in medicine, vol. 53, no 4, pp. 324-328, 2014.

Enlaces | BibTeX

Conferencias

Valenza, G; Orini, M; Citi, L; Minchole, A; Pueyo, E; Laguna, P; Barbieri, R

Assessing Instantaneous QT Variability dynamics within a Point-Process Nonlinear Framework Conferencia

8th CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS, 2014.

Enlaces | BibTeX

Valenza, G; Orini, M; Citi, L; Minchole, A; Pueyo, E; Laguna, P; Barbieri, R

Assessing Real-Time RR-QT Frequency-Domain Measures of Coupling and Causality through Inhomogeneous Point-Process Bivariate Models Conferencia

36nd Annual International Conference of the IEEE EMBS, 2014.

Enlaces | BibTeX

Cruces, P D; Bonomini, M P; Teperino, M J; Mincholé, A; Laguna, P; Arini, P D

Normal Ventricular Repolarization Dispersion Range with Abrupt Heart Rate Changes Conferencia

XLI International Conference on Computing in Cardiology, 2014.

Enlaces | BibTeX

2013

Artículos de revista

Lázaro, J; Gil, E; Bailón, R; Mincholé, A; Laguna, P

Deriving Respiration from Photoplethysmographic Pulse Width Artículo de revista

En: Medical & Biological Engineering & Computing, vol. 51, pp. 233-242, 2013.

Enlaces | BibTeX

53 registros « 1 de 2 »