Faculty Member

Call: +34 976 76 2963

Email: epueyo@unizar.es

Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)

ABOUT ME

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

PUBLICATIONS
300 registros « 2 de 10 »

2022

Artículos de revista

Palmieri, F; Gomis, P; Ferreira, D; Pueyo, E; Martínez, J P; Laguna, P; Ramírez, J

Weighted Time Warping Improves T-wave Morphology Markers Clinical Significance Artículo de revista

En: IEEE Trans Biomed Eng, 2022.

Enlaces | BibTeX

Bukhari, H A; Sánchez, C; Ruiz, J E; Potse, M; Laguna, P; Pueyo, E

Monitoring of Serum Potassium and Calcium Levels in End-stage Renal Disease Patients by ECG Depolarization Morphology Analysis Artículo de revista

En: Sensors, vol. 22, no 2951, 2022.

Enlaces | BibTeX

Albors, C; Lluch, E; Gomez, J F; Cedilnik, N; Mountris, K A; Mansi, T; Khamzin, S; Dokuchaev, A; Solovyova, O; Pueyo, E; Sermesant, M; Sebastian, R; Morales, H G; Camara, O

Meshless electrophysiological modeling of cardiac resynchronization therapy—benchmark analysis with finite-element methods in experimental data Artículo de revista

En: Applied Sciences, vol. 12, no 6438, 2022.

Enlaces | BibTeX

Pueyo, E

Modelización matemática y simulación computacional de la variabilidad espacio-temporal en la actividad eléctrica cardíaca Artículo de revista

En: Rev. Real Academia de Ciencias, vol. 76, pp. 7-54, 2022, ISSN: 0370-3207.

Enlaces | BibTeX

Barrio, R; Martínez, M A; Serrano, S; Pueyo, E

Dynamical mechanism for generation of arrhythmogenic early afterdepolarizations in cardiac myocytes: Insights from in silico electrophysiological models Artículo de revista

En: Physical Review E., vol. 106, no 024402, 2022.

Enlaces | BibTeX

Montero-Calle, P; Flandes-Iparraguirre, M; Mountris, K; Nava, A S; Laita, N; Rosales, R M; Iglesias-García, O; De-Juan-Pardo, E M; Atienza, F; Fernández-Santos, M E; Peña, E; Doblaré, M; Gavira, J J; Fernández-Avilés, F; Prosper, F; Pueyo, E; Vega, M M Mazo

Fabrication of human myocardium using multidimensional modelling of engineered tissues Artículo de revista

En: Biofabrication, 2022.

Enlaces | BibTeX

Monasterio, V; Pueyo, E; Rodríguez-Matas, J F; Carro, J

Cardiac cells stimulated with an axial current-like waveform reproduce electrophysiological properties of tissue fibers Artículo de revista

En: Computer Methods and Programs in Biomedicine, 2022.

Enlaces | BibTeX

Hernández-Vicente, A; Marín-Puyalto, J; Pueyo, E; Vicente-Rodríguez, G; Garatachea, N

Physical activity in centenarians beyond cut-point-based accelerometer metrics Artículo de revista

En: International Journal of Environmental Research and Public Health, 2022.

Enlaces | BibTeX

Mountris, K; Pueyo, E

A meshless fragile points method for rule-based definition of myocardial fiber orientation Artículo de revista

En: Computer Methods and Programs in Biomedicine, vol. 226, no 107164, 2022.

Enlaces | BibTeX

Mountris, K; Dong, L; Guan, Y; Atluri, S N; Pueyo, E

A meshless fragile points method for the solution of the monodomain model for cardiac electrophysiology simulation Artículo de revista

En: Journal of Computational Science, vol. 65, no 101880, 2022.

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Conferencias

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Assessment and optimization of conduction system pacing for anti-bradycardia pacemaker therapy Conferencia

STAFF-MALT Symposium 2022, Senohraby, Czech Republic, 2022.

BibTeX

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres-Pérez, R; Ramos-Marqués, E; Pueyo, E; Ordovás, L

Envejecimiento cardíaco humano: transcriptómica y desarrollo de modelos celulares Conferencia

II Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernández, Elche, 2022.

BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Duwé, S; Ordovás, L; Pueyo, E

Caracterización del remodelado del colágeno asociado a la edad en el ventrículo izquierdo humano de donantes vivos y sus implicaciones en la generación de arritmias Conferencia

XI Jornada de Jóvenes Investigadores del I3A, 2022.

Enlaces | BibTeX

Sales, C; Pueyo, E; Julián, I; Sorinas, L; Cabrera, M; Ruiz, J R; Ramos, J

Cambios en la despolarización y repolarización producidos por la estimulación de rama izquierda frente a la estimulación convencional Conferencia

Ritmo22, Granada, España, 2022.

BibTeX

Melero, J; Sales, C; Julián, I; Ruiz, J R; Pueyo, E; Ramos, J

Estimulación de rama izquierda frente a estimulación de ventrículo derecho: cambios en la despolarización y en la repolarización Conferencia

Congreso de la Salud Cardiovascular, Palma de Mallorca, España, 2022.

BibTeX

Sales, C; Melero, J; Julián, I; Ramos, J; Mincholé, A; Pueyo, E

Comparación de los efectos de la estimulación cardíaca convencional y la estimulación de rama izquierda sobre la despolarización y repolarización ventricular en el ECG Conferencia

Jornadas de Jóvenes Investigadores del I3A, Zaragoza, España, 2022.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Abdollahpur, M; Sandberg, F; Rodriguez-Matas, J F; Laguna, P; Pueyo, E

Effects of Acetylcholine Release Spatial Distribution on the Frequency of Atrial Reentrant Circuits: a Computational Study Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Bukhari, H A; Sánchez, C; Laguna, P; Potse, M; Pueyo, E

Inter-individual differences in cell composition across the ventricular wall may explain variability in ECG response to serum potassium and calcium variations Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Gómez, M; Carro, J; Pueyo, E; Monasterio, V

An in Silico Investigation into the Role of SK Channels in Failing Ventricular Myocytes Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Rosales, R M; Mountris, K; Doblaré, M; Mazo, M; Pueyo, E

Ventricular Conduction System Modeling for Electrophysiological Simulation of the Porcine Heart Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Bukhari, H A; Sánchez, C; Pueyo, E; Potse, M

Accelerating stabilization of whole-heart models after changes in cycle length Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Pérez-Martínez, A; Oliván-Viguera, A; Pueyo, E

La endotelina-1 aumenta la heterogeneidad de la repolarización ventricular en cerdos con infarto crónico de miocardio Conferencia

XI Jornada de Jóvenes Investigadores e Investigadoras del I3A, Zaragoza, España, 2022.

Enlaces | BibTeX

Pérez-Martínez, A; Pueyo, E; Oliván-Viguera, A

Endothelin-1 enhances transmural heterogeneities in healthy porcine ventricular myocardium Conferencia

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

Enlaces | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Bellido-Morales, A; Sorribas-Berjón, J F; Matamala-Adell, M; Vázquez-Sancho, M; Fañanás-Mastral, J; Vallejo-Gil, J M; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Arbonés-Mainar, J M; Pueyo, E

SK channels characterization in the human ventricle: differences in expression levels and electrophysiological role in non-diseased and heart failure ventricles Conferencia

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; Pueyo, E

Endothelin-1 amplifies ventricular repolarization heterogeneities in chronic myocardial infarction pigs Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

Enlaces | BibTeX

Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Pueyo, E; Oliván-Viguera, A

SK channels contribution to ventricular electrophysiology in heart failure patients Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

Enlaces | BibTeX

Pérez-Martínez, A; Bellido-Morales, A; Fañanás-Mastral, J; Matamala-Adell, M; Sorribas-Berjón, J F; Vallejo-Gil, J M; Vázquez-Sancho, M; Ballester-Cuenca, C; Oliván-Viguera, A; Pueyo, E

Caracterización del papel de los canales SK en el remodelado ventricular producido por insuficiencia cardíaca Conferencia

II Congreso Anual Internacional de Estudiantes de Doctorado (CAED), Elche, España, 2022.

BibTeX

Oliván-Viguera, A; García-Otín, A L; Lozano-Gerona, J; Abarca-Lachen, E; García-Malinis, A J; Hamilton, K L; Gilaberte, Y; Pueyo, E; Köhler, R

Cell damage and apoptosis induced by TRPV4 activation in human melanoma cells and Hacat keratinocytes Conferencia

Reunión Anual de Sociedades de Biociencias 2022, Reunión conjunta SAIC SAI & FAIC SAFIS 2022, Medicina. Buenos Aires, Vol. 82 Supl. V – 2022 Buenos Aires, Argentina, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; García-Mendivil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age related cardiotoxicity of drugs Conferencia

Stem cells and stem cell models in disease & health (SCMiDH), Hasselt, Belgium, 2022.

Enlaces | BibTeX

300 registros « 2 de 10 »