Faculty Member

Call: +34 976 76 2963

Email: epueyo@unizar.es

Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)

ABOUT ME

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

PUBLICATIONS
300 registros « 4 de 10 »

2021

Conferencias

Celotto, C; Sánchez, C; Mountris, K; Laguna, P; Pueyo, E

Rotor Termination in Cholinergic Paroxysmal Atrial Fibrillation by Small-Conductance Calcium-Activated K+ Channels Inhibition and Isoproterenol: a Computational Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

Cebollada, R; Pérez-Martínez, C; Mountris, K; Martínez, J P; Laguna, P; Pueyo, E

Mechanisms Underlying QT Interval Adaptation Behind Heart Rate During Stress Test Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

Rosales, R M; Mountris, K; Doblaré, M; Mazo, M; Pueyo, E

In silico Electrophysiological Evaluation of Scaffold Geometries for Cardiac Tissue Engineering Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

García, D; Kontaxis, S; Hernández-Vicente, A; Hernando, D; Milagro, J; Pueyo, E; Garatachea, N; Bailón, R; Lázaro, J

Ventilatory Thresholds Estimation Based on ECG-derived Respiratory Rate Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

Pérez, M; García-Mendívil, L; Mountris, K; Smisdom, N; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Matamala-Adell, M; Vázquez-Sancho, M; Mancebón-Sierra, F Javier; Vaca-Núñez, A Sebastián; Ballester-Cuenca, C; Olivan-Viguera, A; Ordovás, L; Pueyo, E

Age-associated changes in fibrosis amount and spatial organization and its effects on human ventricular electrophysiology Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

García-Mendívil, L; Smisdom, N; Duwe, S; Mountris, K; Srinivasan, S; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Olivan-Viguera, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, F; Ballester-Cuenca, C; Diez, E; Ordovás, L; Pueyo, E

Caracterización del remodelado cardiaco asociado a la edad en el ventrículo izquierdo humano Conferencia

Primer congreso anual de estudiantes de doctorado de la Universidad Miguel Hernández. Comunicación oral, 2021.

BibTeX

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

Envejecimiento cardiaco humano: transcriptómica y desarrollo de modelos celulares de envejecimiento Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Mountris, K A; Laguna, P; Pueyo, E

Efectos Transitorios y en Estado Estacionario del Bloqueo del Canal SK y de la Estimulación Adrenérgica para Contrarrestar los Efectos Arritmogénicos Inducidos por Acetilcolina en la Aurícula Humana: un Estudio Computacional Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

Pérez-Martínez, A; Oliván-Viguera, A; Pueyo, E

Contribución de los canales SK a la electrofisiología ventricular humana en pacientes con insuficiencia cardíaca Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

Bukhari, H A; Sánchez, C; Potse, M; Laguna, P; Pueyo, E

Estimación del nivel de potasio en sangre mediante las pendientes del QRS del electrocardiograma en pacientes renales crónicos Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Laguna, P

Mejora de la delineación del intervalo QT en señales ECG grabadas durante prueba de esfuerzo Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

In vivo and in vitro cardiac aging: developing of cellular aging models Conferencia

XIX Congreso de la Sociedad Española de Biología Celular. Póster, 2021.

BibTeX

Mountris, K A; Doblaré, M; Pueyo, E

Image-based Cardiac Electrophysiology Simulation through the Meshfree Mixed Collocation Method Conferencia

43st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2021.

Enlaces | BibTeX

2020

Artículos de revista

Sampedro-Puente, D A; Fernandez-Bes, J; Szentandrássy, N; Nánási, P; Taggart, P; Pueyo, E

Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis Artículo de revista

En: Front. Physiol, vol. 10, no 1547, 2020.

Enlaces | BibTeX

Corral-Acero, J; Margara, F; Marciniak, M; Rodero, C; Loncaric, F; Feng, Y; Gilbert, A; Fernandes, J F; Bukhari, H A; Wajdan, A; Villegas-Martinez, M; Sousa-Santos, M; Shamohammdi, M; Luo, H; Westphal, P; Leeson, P; DiAchille, P; Gurev, V; Mayr, M; Geris, L; Pathmanathan, P; Morrison, T; Cornelussen, R; Prinzen, F; Delhaas, T; Doltra, A; Sitges, M; Vigmond, E J; Zacur, E; Grau, V; Rodriguez, B; Remme, E W; Niederer, S; Mortier, P; McLeod, K; Potse, M; Pueyo, E; Bueno-Orovio, A; Lamata, P

The ‘Digital Twin’ to enable the vision of precision cardiology Artículo de revista

En: European Heart Journal, 2020.

Enlaces | BibTeX

Sánchez, F J; Gonzalez, V A; Farrando, M; Jayat, A O Baigorria; Segovia-Roldan, M; García-Mendívil, L; Ordovás, L; Prado, N J; Pueyo, E; Diez, E R

Atrial Dyssynchrony Measured by Strain Echocardiography as a Marker of Proarrhythmic Remodeling and Oxidative Stress in Cardiac Surgery Patients Artículo de revista

En: Oxidative Medicine and Cellular Longevity, vol. ID 8895078, 2020.

Enlaces | BibTeX

Prado, N J; Muñoz, E M; Farias-Altamirano, L E; Aguiar, F; Ponce-Zumino, A Z; Sánchez, F J; Miatello, R M; Pueyo, E; Diez, E R

Reperfusion Arrhythmias Increase After Superior Cervical Ganglionectomy Due To Conduction Disorders And Changes In Repolarisation Artículo de revista

En: International Journal of Molecular Sciences, vol. 21, no 5, pp. 1804, 2020.

Enlaces | BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

Characterization of Spatio-Temporal Cardiac Action Potential Variability at Baseline and under Beta-Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction Artículo de revista

En: IEEE Journal of Biomedical and Health Informatics, vol. 25, no 1, pp. 276-288, 2020.

Enlaces | BibTeX

Lozano-Gerona, J; Olivan-Viguera, A; Delgado-Wicke, P; Singh, V; Brown, B M; Tapia-Casellas, E; Pueyo, E; Valero, Sofía M; Garcia-Otín, A L; Giraldo, P; Abarca-Lachen, E; Surra, J C; Osada, J; Hamilton, K L; Raychaudhuri, S P; Marigil, M; Juarranz, A; Wulff, H; Miura, H; Gilaberte, Y; Köhler, R

Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis Artículo de revista

En: PlosOne, vol. 15, no 3, pp. e0222619, 2020.

Enlaces | BibTeX

Barrio, R; Coombes, S; Fenton, Desrochesand M F; Luther, S; Pueyo, E

Excitable Dynamics in Neural and Cardiac Systems Artículo de revista

En: Communications in Nonlinear Science and Numerical Simulation, 2020.

Enlaces | BibTeX

Barrio, R; Martínez, M A; Pérez, L; Pueyo, E

Bifurcations and slow-fast analysis in a cardiac cell model for investigation of early afterdepolarizations Artículo de revista

En: Mathematics, vol. 8, no 6, pp. 880, 2020.

Enlaces | BibTeX

Nanasi, P P; Pueyo, E; Virag, L

Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes Artículo de revista

En: Frontiers in Pharmacology, 2020.

Enlaces | BibTeX

Hernández-Vicente, A; Hernando, D; Santos-Lozano, A; Rodríguez-Romo, G; Vicente-Rodríguez, G; Pueyo, E; Bailón, R; Garatachea, N

Heart rate variability and exceptional longevity Artículo de revista

En: Frontiers in Physiology, 2020.

Enlaces | BibTeX

Bragard, J R; Camara, O; Echebarria, B; Giorda, L Gerardo; Pueyo, E; Saiz, J; Sebastián, R; Soudah, E; Vázquez, M

Cardiac Computational Modelling Artículo de revista

En: Rev Esp Cardiol, vol. 74, no 1, pp. 65-71, 2020.

Enlaces | BibTeX

Oliver-Gelabert, A; García-Mendívil, L; Vallejo-Gil, J M; Fresneda-Roldán, P C; Andelová, K; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, F; Ballester-Cuenca, C; Tribulova, N; Ordovás, L; Diez, E R; Pueyo, E

Automatic quantification of cardiomyocyte dimensions and connexin 43 lateralization in fluorescence images Artículo de revista

En: Biomolecules, vol. 10, no 9, pp. 1334, 2020.

Enlaces | BibTeX

Milagro, J; Hernández-Vicente, A; Hernando, D; Casajús, J A; Garatachea, N; Bailón, R; Pueyo, E

Estimation of the second ventilatory threshold through ventricular repolarization profile analysis Artículo de revista

En: Scand J Med Sci Spo, vol. 31, pp. 339-349, 2020.

Enlaces | BibTeX

Mountris, K A; Pueyo, E

The Radial Point Interpolation Mixed Collocation Method (RPIMC) for the solution of transient diffusion problems Artículo de revista

En: Eng Anal Bound Elem, vol. 121, pp. 207–216, 2020.

Enlaces | BibTeX

Oliván‑Viguera, A; Pérez‑Zabalza, M; García‑Mendívil, L; Mountris, K A; Orós‑Rodrigo, S; Ramos‑Marquès, E; Vallejo‑Gil, J M; Fresneda‑Roldán, P C; Fañanás‑Mastral, J; Vázquez‑Sancho, M; Matamala‑Adell, M; Sorribas‑Berjón, F; Bellido‑Morales, J A; Mancebón‑Sierra, F J; Vaca‑Núñez, A S; Ballester‑Cuenca, C; Marigil, M A; Pastor, C; Ordovás, L; Köhler, R; Diez, E; Pueyo, E

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors Artículo de revista

En: Sci Rep, vol. 10, no 19941, 2020.

Enlaces | BibTeX

Conferencias

Celotto, C; Sanchez, C; Mountris, K A; Laguna, P; Pueyo, E

SK Channel Block and Adrenergic Stimulation Counteract Acetylcholine-Induced Arrhythmogenic Effects in Human Atria Conferencia

42st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Laguna, P

Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings Conferencia

11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO), 2020.

Enlaces | BibTeX

300 registros « 4 de 10 »