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Pablo Laguna

Funding agency

Ref: 062

The Biomedical Signal Interpretation and Computational Simulation (BSICoS) group focuses its  activity on the processing, interpretation and Computer Simulation of biomedical signals. The main objective of the group is the development of methods for biomedical signal processing, driven by the physiology, for personalized interpretation (diagnosis, prognosis and therapy) of the conditions of the cardiovascular, respiratory and autonomic nervous systems and their interactions. The goal is to improve the impact of ICTs in health and further  understanding  the functioning of biological systems that can be observed through noninvasive signals. Key to this is working with clinical teams and research groups that combine the experiences of the two areas, direct research to solve relevant clinical problems and facilitate the transfer of results to clinical practice. All this is embodied in six application domains that constitute the lines of work of the group:

1) Modeling and simulation of cardiac electrophysiology.

2) noninvasive ECG markers based on the conditions for characterization and identification of arrhythmic risk.

3) Signal processing of intracardiac electrogram (EGM) to improve planning and therapy of cardiac interventions.

4) non-invasive evaluation of the activity of the autonomic nervous system (ANS) quantification.

5) Processing and characterization of biomedical signals in respiratory diseases.

6) Caracterización experimental y modelado in-vitro del envejecimiento cardiaco.


The lines of research addressed by the Group pursued basic scientific and technological progress through the development of algorithms and methods to improve diagnosis, prognosis and therapy application in cardiorespiratory and autonomic nervous system diseases, as well as a better understanding of physiology pathological or not pathological situations (drowsiness, stress, microgravity, etc).