EXPERIMENTAL CHARACTERIZATION AND IN-VITRO MODELING OF CARDIAC AGING

• Technology 1

Cardiac biomarkers as non-invasive tools to predict heart dysfunction in relation to age, heart damage or disease.

Targeting sector: Pharmaceutical and diagnostics companies.

• Technology 2

Discovery of cardiac anti-aging interventions for the development of novel therapies.

Targeting sector: Pharmaceutical companies

Human iPSC cell culture lab and genome engineering techniques

Optical Mapping (MiCAM O5-Ultima CMOS camera, SciMedia, Costa Mesa, CA) for electrophysiological recording

Vibratome (VT12000 s, LEICA) for the preparation of myocardial tissue slices

Mechanical electrostimulation system (C-Strecht and C-Pace M, Ion Optix) for organotypic tissue and cell culture