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Clara Sales, BSiCoS group researcher, presented two abstracts at the EHRA Conferenceand Julia Ramírez was invited to be part of the jury members Clara Sales presented two abstracts at the EHRA 2023 conference focused on the analysis of electrocardiograms (ECGs) from patients suffering from bradycardia who had an indication for pacemaker implantation. Patients had been treated with either the conventional right ventricular pacing (RVP) or the recently proposed left bundle branch area pacing (LBBAP). RVP has been the treatment of…

The “Tercer Milenio” Awards have been recognizing the Aragonese research community for eight years, from the youngest to the most consolidated trajectories, with knowledge transfer, innovation and scientific dissemination. The Paraninfo of the University of Zaragoza hosted the event in which the researcher Julia Ramírez García, from the BSiCoS group, received the "Young Research Talent" award for her work in biomedical signal processing. In addition, the Government of Aragon has awarded her the Aragón Investiga Prize for Young Researchers "William…

Julia Ramírez, BSiCoS group researcher, participated in the Congress of the European Society of Cardiology. She was invited to present her latest work on Sudden Cardiac Death (SCD) prediction using a new index, TMV, derived from a single heartbeat from a single lead on the electrocardiogram (ECG) signal. Her talk was part of the "Late-Breaking Basic and Translational Science" session, where Julia showed her results demonstrating that TMV is the only ECG marker measured at rest that associates with malignant…

Julia Ramírez presented a poster at the European Human Genetics Conference describing new findings on rare variants modulating resting heart rate and their importance in cardiovascular risk. In addition, in the first days of June, she participated in the ERAS World Congress 2022 (Enhanced Recovery After Surgery). She was invited to give a talk describing the potential of artificial intelligence algorithms for predicting and reducing risk. Previously, in May,  Julia Ramírez gave an oral presentation at the European Atherosclerosis Society (EAS 2022) showing the added value…

Necesitamos voluntarios para un estudio de investigación sobre depresión y estrés que desarrollan el Instituto de Investigación Sanitaria de Aragón (IIS Aragón) y el Instituto de Investigación en Ingeniería de Aragón (I3A) de la Universidad de Zaragoza. En estudios anteriores hemos comprobado el potencial de marcadores fisiológicos, relacionados con la frecuencia cardiaca, la morfología del pulso cardiaco, la sudoración, la cadencia del habla, etc. para identificar sujetos con depresión.  Nuestro objetivo ahora es estudiar la viabilidad de monitorizar la depresión mediante…

Raquel Bailón y Esther Pueyo participaron en el Observatorio en Red para el Estudio y la Prevención de la Muerte Súbita en el Deporte (PREMUBID) Raquel Bailón y Esther Pueyo, investigadoras del grupo BSICoS, dieron una charla sobre la importancia del análisis del electrocardiograma (ECG) en deportistas y el estudio de marcadores de riesgo de muerte súbita cardíaca el 5de noviembre en el Observatorio Científico en Red para el Estudio y la Prevención de la Muerte Súbita en el Deporte…

Allí, acaba de presenter su trabajo “Eigenvector-based spatial ECG filtering improved QT delineation in stress test recordings” Explica Cristina Pérez que, actualmente, se estudian las características de las diferentes curvas que componen la señal de electrocardiograma (ECG), así como sus puntos característicos, con la idea de definir biomarcadores sin la necesidad de recurrir a pruebas invasivas. Entre ellos, un mayor tiempo de adaptación del intervalo QT ante cambios abruptos de la variabilidad del ritmo cardiaco (HR) se ha definido como…

Laura García, member of the BSiCoS Group, presents her research at the Spanish Cell Biology Society (SEBC) Congress Age is one of the most relevant predisposing risk factors for cardiovascular diseases. Aged hearts undergo structural and functional changes that are orchestrated at the molecular level. The molecular basis is poorly characterized in humans due to the scarcity of tissue samples and human models. We aim to study transcriptome dynamics of the aging human left ventricle (LV) according to both chronological…

Pablo Laguna, BSiCoS researcher, gave a talk about Physiologically driven biomedical signal processing at the Faculty of Physics at the Autonomous University of San Luis Potosí (UASLP) in Mexico. During his online conference, he explaned how biomedical signals convey information about biological systems and can emanate from sources of as varied origins as electrical, mechanical or chemical. In particular, biomedical signals can provide relevant information on the function of the human body. This information, however, may not be apparent in…

Atrial Signals 2021: Modeling the aging of the heart Cardiovascular diseases (CVDs) are responsible for more than four million deaths per year in Europe. The single major risk factor for CVD is age, which leads to a progressive decline in the physiological functions of the body, with very notable effects on the heart. These effects are associated with enhanced predisposition to cardiac arrhythmias. In this presentation, integrative approaches combining in silico modeling with in vitro cell and tissue analysis and…

“Ventilatory Thresholds Estimation Based on ECG-derived Respiratory Rate” is the work presented by Diego García, BSiCoS researcher, at the Compunting in Cardiology Conference, held in Brno (Czech Republic) between 12 and 15 September. Young Researcher Award (YIA) finalist. The purpose of this work is to study the feasibility of estimating the first and second ventilatory thresholds (VT1 and VT2, respectively) by using electrocardiogram (ECG)-derived respiratory rate during exercise testing. The ECGs of 25 healthy volunteers during cycle ergometer exercise test…

Aging is the main risk factor for cardiovascular diseases. In humans, cardiac aging remains poorly characterized. Most studies are based on chronological age (CA) and disregard biological age (BA), the actual physiological age (result of the aging rate on the organ structure and function), thus yielding potentially imperfect outcomes. Deciphering the molecular basis of ventricular aging, especially by BA, could lead to major progresses in cardiac research. We aim to describe the transcriptome dynamics of the aging left ventricle (LV)…

Morphological changes in pulse rate could provide complementary information to that extracted from the pulse rate variability on the response of the cardiovascular and nervous systems of subjects exposed to hyperbaric environments. The peripheral activation produces a vasoconstriction that increases the pulse width and area. However, the pulse width of the anacrotic phase seems to be a better marker in the variation of peripheral vascular resistance than the pulse width. Pelaez-Coca, M D; Hernando, A; Lozano, M T; Sanchez, C;…

Chronic kidney disease affects more than 10% of the world population. Changes in serum ion concentrations increase the risk for ventricular arrhythmias and sudden cardiac death, particularly in end stage renal disease (ESRD) patients. We characterized how T wave amplitude, duration and morphology descriptors change with variations in serum levels of potassium and calcium and in heart rate, both in ESRD patients and in simulated ventricular fibers. Electrocardiogram (ECG) recordings from twenty ESRD patients undergoing hemodialysis (HD) and pseudo-ECGs (pECGs)…

Electrocardiogram (ECG) has been regarded as a source of respiratory information with the main focus in the estimation of the respiratory rate. Although little research concerning the estimation of tidal volume (TV) has been conducted, there are several ECG-derived features that have been related with TV in the literature, such as ECG-derived respiration, heart rate variability or respiratory rate. In this work, we exploited these features for estimating TV using a linear model. 25 young (33.4 ± 5.2 years) healthy male volunteers were recruited for performing…

This year, we will virtually attend the XXXVII Annual Congress of the Spanish Society of Biomedical Engineering (CASEIB) between November 25 and 27. Five of our researchers will defend the work carried out in our research group. CASEIB is a national reference forum for exchanging knowledge and experiences and promoting R + D + i in Biomedical Engineering. This is the BSiCoS group participation program: November 25 “Delay between QT and RR in stress test records as an indicator of…

Next Monday and Tuesday, November 16 and 17, we will attend the XIV CIBER-BBN Annual Conference. Our research group will be represented by Pablo Armañac and Alejando Alcaine, who will present their research work at this meeting that, this year, will be online.   Pablo Armañac will participate with his work "Autonomic nervous system surrogates, cardiopulmonary coupling and respiratory parameters as predictors of successful weaning in mechanically ventilated patients (ANS-RESP-WEANING)", on Monday at 12:45.   Alejandro Alcaine, will speak on…

PhD contract and topic A PhD contract (former FPI program) is offered for a PhD position at the Biomedical Signal Interpretation and Computational Simulation (BSICoS) group of the Aragón Institute of Engineering Research, University of Zaragoza. The PhD thesis is associated with the research grant “Towards improved management of cardiovascular diseases by integrative in silico-in vitro-in vivo research into heart’s structure, function and autonomic regulation”, funded by Spanish Ministry of Science and Innovation, with reference PID2019-105674RB-I00. As part of his/her…