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Research line

The objective of this line is the extraction of  relevant cardiovascular and respiratory information from wearable devices, such as the heart rate, its variability (HRV), respiratory rate, and tidal volume, and its application to cardiovascular and/or respiratory pathologies as well as wellbeing monitoring. This includes:

  1. Coverage studies.
  2. Techniques for maximizing the coverage.
  3. Development and/or adaptation of methods for extracting cardiovascular and/or respiratory information from wearable devices.
  4. Applications that may benefit from a long-term monitoring, such as sleep studies, chronic respiratory diseases, daily monitoring of stress, ambulatory monitoring of depression, among others.

Investigator in charge

Jesús Lázaro Plaza

Jesús Lázaro Plaza

Technologies and targeting sectors

Technologies:

  • Framework for extracting physiological information from PPG:
      • Robust PPG pulse detector.
      • PPG-derived respiration technique that is robust againist sympathetic (LF) noise.
      • Physiology-driven PPG pulse decomposition analysis technique
      • PPG-based baroreflex sensitivity estimation technique
  • PPG-based obstructive sleep apnea syndrome detection in children.
  • Robust ECG-derived respiration technique, evaluated, among others, with exercise stress test recordings and with recordings from a wearable armband.


Targeting sector:

  • Companies interested in ambulatory/wearable solutions for cardiorespiratory monitoring.

Singular equipment

Biomedical acquisition lab, including:

  • Tilt table set
  • Finometer for Blood pressure measurement
  • BIOPAC system for data acquisition

 

Ambulatory biomedical signals acquisition equipment, including:

  • Holter devices
  • Polysomnography system SOMTE PSG V2
  • Medicom ABP 10, including sensors for ECG, PPG, EMG, respiration, EDA, etc.

 

Wearable devices:

  • ECG-wearable armband prototype developed at University of Connecticut
  • AppleWatch
  • Polar OH1

Patents and technology transfer

  • Technology transfer agreement with Volumetrix LLC (Nashville, TN, USA) on validation of pulse rate variability, respiratory frequency and stress assessment from NIVAband.
  • Consulting agreement with Gideon Health INC (DE, USA) on physiology-driven signal processing techniques for wearable devices.
  • Technology transfer agreement with Brainmatterz LLC (McKinney, TX, USA) on ambulatory/wearable solutions for sleep apnea monitoring.

Projects

Towards improved management of cardiovascular diseases by integrative in silico-in vitro-in vivo research into hearts structure, function and autonomic regulation – PID2019-105674RB-I00

Towards improved management of cardiovascular diseases by integrative in silico-in vitro-in vivo research into hearts structure, function and autonomic regulation – PID2019-105674RB-I00

Closed-loop stimulation of the central nervous system to modulate tremoroscillations in the motor nervous system: PID-2022-138585OA-C32

Closed-loop stimulation of the central nervous system to modulate tremoroscillations in the motor nervous system: PID-2022-138585OA-C32

JIUZ2022-IAR-02: Respiration monitoring by means of a wrist-worn wearable device prototype

JIUZ2022-IAR-02: Respiration monitoring by means of a wrist-worn wearable device prototype

UZ2022-IAR-06: Towards a system for diagnosis and monitoring sleep apnea-hypopnea syndrome at home based on a wearable armband

UZ2022-IAR-06: Towards a system for diagnosis and monitoring sleep apnea-hypopnea syndrome at home based on a wearable armband

Implementation of wearable technology in primary health care for personalized exercise medicine (WearablePerMed) – PMP22/00002

Implementation of wearable technology in primary health care for personalized exercise medicine (WearablePerMed) – PMP22/00002

Major Depressive Disorder monitoring system: development of a platform based on wearable devices in relevant scenarios – PDC2022-133197-I00

Major Depressive Disorder monitoring system: development of a platform based on wearable devices in relevant scenarios – PDC2022-133197-I00

Monitoring and assessment of obstructive sleep apnea and its outcomes through the processing of physiological signals of wearables – PID2021-126734OB-C21

Monitoring and assessment of obstructive sleep apnea and its outcomes through the processing of physiological signals of wearables – PID2021-126734OB-C21

Tidal Volume Monitoring by a Wearable Armband

Tidal Volume Monitoring by a Wearable Armband

Consulting services for basic physiologic features

Consulting services for basic physiologic features

Finished Projects

PPG-based sleep apnea monitoring

Physiologically guided signal analysis for ambulatory monitoring of depression

Characterization and modeling of the physiological response in variable hyperbaric environments

Improved monitoring of the autonomic nervous system during daily life applied to stress, depression and exercise

Biomedical monitoring prototype integrated in diving equipment for underwater environment

Improvement of a device for real-time monitoring of the photoplestimographic signal in hyperbaric environments

Validation of pulse rate variability, respiratory frequency and stress assessment from NIVAband

WECARMON: Wearable Cardiorespiratory Monitor

Optimization of a submersible device for monitoring the photoplesthymographic signal

Remote Assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS)

Design and validation of a submersible device for the monitoring of the Autonomous Nervous System through the recording of pulse photoplethysmography in aquatic activities