-
Projects
Clinically-guided data processing methods and in silico models to improve patient stratification and therapy response in cardiac and neurological disorders: PID2022-140556OB-I00
Start date
2023
End date
2026
Coordinator
Esther Pueyo / Juan Pablo Martínez
Funding agency
Agencia Estatal de Investigación
The project aims at delivering novel technologies, in the form of data processing methods and in silico models, which are expected to be implemented clinically to promote the health of patients with cardiac and neurological disorders. We will focus on three diseases that affect millions of people worldwide: diabetes mellitus, atrial fibrillation and stroke. We will develop novel multi-modal, multi-scale, multi-approach tools for the analysis of experimental, clinical and computational data.
2023
García-Mendívil, L; Pérez-Zabalza, M; Duwé, S; Ordovás, L; Pueyo, E
Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy Journal Article
In: Star Protocols, vol. 4, no. 102730, 2023.
@article{GarciaMendivil23c,
title = {Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy},
author = {L García-Mendívil and M Pérez-Zabalza and S Duwé and L Ordovás and E Pueyo},
url = {https://drive.google.com/file/d/1b0Z65PwpGV4xaLROXC93AsXDZ5Jc-zL7/view},
doi = {10.1016/j.xpro.2023.102730},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
journal = {Star Protocols},
volume = {4},
number = {102730},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
García-Mendívil, L; Pérez-Zabalza, M; Oliver-Gelabert, A; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; André-Bellido, J A; Vaca-Núñez, A S; Ballester-Cuenca, C; Diez, E R; Ordovás, L; Pueyo, E
Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk Journal Article
In: Research, vol. 6, iss. 0254, 2023.
@article{GarciaMendivil23b,
title = {Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk},
author = {L García-Mendívil and M Pérez-Zabalza and A Oliver-Gelabert and J M Vallejo-Gil and J Fañanás-Mastral and M Vázquez-Sancho and J A André-Bellido and A S Vaca-Núñez and C Ballester-Cuenca and E R Diez and L Ordovás and E Pueyo},
url = {https://drive.google.com/file/d/1rJSQdUDM8D6w9wiiOm1_bqZVOEQ8RNxX/view},
doi = {10.34133/research.0254 },
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
journal = {Research},
volume = {6},
issue = {0254},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mountris, K A; Pueyo, E
Cardiac electrophysiology meshfree modeling through the Mixed Collocation Method Journal Article
In: Applied Sciences, vol. 13, no. 11460, 2023.
@article{Mountris23,
title = {Cardiac electrophysiology meshfree modeling through the Mixed Collocation Method},
author = {K A Mountris and E Pueyo},
url = {https://drive.google.com/file/d/1GFVkXNHE9Lp2eZ40Nv6D2uf255-BPThR/view},
doi = {10.3390/app132011460},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
journal = {Applied Sciences},
volume = {13},
number = {11460},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Velarte, A; Otin, A; Giménez-Gómez, P; Muñoz-Berbel, X; Pueyo, E
Fiber optic-based system for high-resolution monitoring of stretch in excised tissues Journal Article
In: Biosensors, vol. 13, no. 900, 2023.
@article{Velarte23,
title = {Fiber optic-based system for high-resolution monitoring of stretch in excised tissues},
author = {A Velarte and A Otin and P Giménez-Gómez and X Muñoz-Berbel and E Pueyo},
url = {https://drive.google.com/file/d/1A7YZHYZ0v2QeWEJfTcLmnLPx8kgt1dAm/view},
doi = {10.3390/bios13100900},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
journal = {Biosensors},
volume = {13},
number = {900},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Ramírez, J; Miguel, A; Duijvenboden, S; Orini, M; Young, W; Tinker, A; Lambiase, P; Munroe, P; Martínez, J P
Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.
@conference{Ramirezc23,
title = {A Multi-layer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population},
author = {J Ramírez and A Miguel and S Duijvenboden and M Orini and W Young and A Tinker and P Lambiase and P Munroe and J P Martínez},
url = {https://drive.google.com/file/d/1UaE_QTuO0CUh9wNV7N1s1zA1ByymE0HA/view},
doi = {10.22489/CinC.2023.342},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {Proceedings of the XLIX International Conference on Computing in Cardiology},
address = {Atlanta, USA},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Rosales, R; Mountris, K; Doblaré, M; Mazo, M; Pueyo, E
Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.
@conference{Rosalesc23,
title = {In Silico Assessment of Arrhythmic Risk in Infarcted Ventricles Engrafted with Engineered Heart Tissues},
author = {R Rosales and K Mountris and M Doblaré and M Mazo and E Pueyo},
url = {https://drive.google.com/file/d/1bYO-c8Q96R65_jDhjpjTn8aElrjqV6vt/view},
doi = {10.22489/CinC.2023.275},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {Proceedings of the XLIX International Conference on Computing in Cardiology},
address = {Atlanta, USA},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Javierre, M; Kloostermann, M; Dam, P Van; Eijsvogels, T; Pueyo, E; Bailón, R
Análisis de la variabilidad de la frecuencia cardíaca en maratonianos Conference
VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Cartagena, España, 2023.
@conference{javierre_c23,
title = {Análisis de la variabilidad de la frecuencia cardíaca en maratonianos},
author = {M Javierre and M Kloostermann and P {Van Dam} and T Eijsvogels and E Pueyo and R Bailón},
url = {https://drive.google.com/file/d/1mV_ZvzZLYNAufRcfWgPDyY48jApzWz9w/view},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB},
pages = {18-21},
address = {Cartagena, España},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Gómez-Fonseca, N; Ramírez, J; Martín-Yebra, A; Platonov, P; Martínez, J P; Laguna, P
XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.
@conference{Gomezc23b,
title = {Los cambios en la morfología del intervalo Tpico-Tfin medidos mediante time-warping se asocian con la fibrilación ventricular inducida por la isquemia en un modelo porcino},
author = {N Gómez-Fonseca and J Ramírez and A Martín-Yebra and P Platonov and J P Martínez and P Laguna},
url = {https://papiro.unizar.es/ojs/index.php/jji3a/article/view/9065},
doi = {10.26754/jjii3a.20239065},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
García-Mendívil, L; Pérez, M; Rosales, R; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Ordovás, L; Pueyo, E
Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.
@conference{GarciaMendivilc23,
title = {Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia},
author = {L García-Mendívil and M Pérez and R Rosales and J M Vallejo-Gil and J Fañanás-Mastral and M Vázquez-Sancho and J A Bellido‑Morales and A S Vaca‑Núñez and C Ballester-Cuenca and L Ordovás and E Pueyo},
url = {https://drive.google.com/file/d/1bG2n4bELCw9cB46GjZ40jgPpSd9zlVvw/view},
doi = {10.22489/CinC.2023.352},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {Proceedings of the XLIX International Conference on Computing in Cardiology},
address = {Atlanta, USA},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Bueno-Palomeque, F L; Mountris, K; Ortigosa, N; Bailón, R; Bijnens, B; Crispi, F; Pueyo, E; Mincholé, A; Laguna, P
Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.
@conference{Buenoc23,
title = {QRS Width and T-peak to T-end Interval Are Prolonged in Preadolescents with Severe Intrauterine Growth Restriction at Birth When Compared to Controls},
author = {F L Bueno-Palomeque and K Mountris and N Ortigosa and R Bailón and B Bijnens and F Crispi and E Pueyo and A Mincholé and P Laguna},
url = {https://drive.google.com/file/d/1a0oqF4thCHqyFQavWsgrbW_puUl1cns-/view},
doi = {10.22489/CinC.2023.344},
year = {2023},
date = {2023-01-01},
urldate = {2023-01-01},
booktitle = {Proceedings of the XLIX International Conference on Computing in Cardiology},
address = {Atlanta, USA},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}