Confocal microscope with high performance Light Sheet based system and toxicity assessment platform

The action involves the acquisition of a Light Sheet confocal microscope together with a high-performance platform for toxicity assessment. The platform consists of a high-content confocal microscopy system, a microelectrode array equipment, an automated patch-clamp system and an optical force transducer. Together they will enable cutting-edge research into multi-parametric analysis of cell and tissue processes and their interrelationship to explain differences between states such as health and disease using primary or iPSC-derived cells from healthy donors or patients. Phenotypic changes in response to a screening compound under different pathological states will be identified, thus facilitating identification of new therapies. The equipment will greatly contribute to improve competences in safety and toxicity analysis of compounds and materials and it will expand current knowledge on basic mechanisms of disease and therapy effects, among other possible fields of study.