Faculty Member

Call: +34 976 76 2963

Email: epueyo@unizar.es

Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)

ABOUT ME

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

PUBLICATIONS
310 registros « 1 de 11 »

2024

Artículos de revista

Celotto, C; Sánchez, C; Abdollahpur, M; Sandberg, F; Rodríguez, J F; Laguna, P; Pueyo, E

The Frequency of Atrial Fibrillatory Waves is Modulated by the Spatiotemporal Pattern of Acetylcholine Release: a 3D Computational Study Artículo de revista

En: Front. Physiol., vol. 14, no 1189464, 2024.

Enlaces | BibTeX

Rosales, R M; Mountris, K A; Oliván-Viguera, A; Pérez-Zabalza, M; Cedillo-Servin, G; Iglesias-García, O; Hrynevich, A; Castilho, M; Malda, J; Prósper, F; Doblaré, M; Mazo, M M; Pueyo, E

Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction Artículo de revista

En: Computers in Biology and Medicine, vol. 171, no 108044, 2024.

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2023

Artículos de revista

Garatachea, N; Pueyo, E; Eijsvogels, T

Prevention of sudden death in sports: a global and multidisciplinary observatory for scientific research and knowledge transfer Artículo de revista

En: Reviews in Cardiovascular Medicine, vol. 24, iss. 1, no 12, 2023.

Enlaces | BibTeX

Pérez, C; Cebollada, R; Mountris, K A; Martínez, J P; Laguna, P; Pueyo, E

The Role of β-adrenergic Stimulation in QT Interval Adaptation to Heart Rate During Stress Test Artículo de revista

En: Plos One, 2023.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Mountris, K A; Laguna, P; Pueyo, E

Steady-State and Transient Effects of SK Channel Block and Adrenergic Stimulation to Counteract Acetylcholine-Induced Arrhythmogenic Effects in the Human Atria: A Computational Study Artículo de revista

En: Computers in Biology and Medicine, 2023.

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Pérez, C; Pueyo, E; Martínez, J P; Viik, J; Laguna, P

QT Interval Time Lag in Response to Heart Rate Changes During Stress Test for Coronary Artery Disease Diagnosis Artículo de revista

En: Biomedical Signal Processing and Control, vol. 86, no 105056, 2023.

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García-Mendívil, L; Pérez-Zabalza, M; Oliver-Gelabert, A; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; André-Bellido, J A; Vaca-Núñez, A S; Ballester-Cuenca, C; Diez, E R; Ordovás, L; Pueyo, E

Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk Artículo de revista

En: Research, vol. 6, iss. 0254, 2023.

Enlaces | BibTeX

Velarte, A; Otin, A; Giménez-Gómez, P; Muñoz-Berbel, X; Pueyo, E

Fiber optic-based system for high-resolution monitoring of stretch in excised tissues Artículo de revista

En: Biosensors, vol. 13, no 900, 2023.

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Mountris, K A; Pueyo, E

Cardiac electrophysiology meshfree modeling through the Mixed Collocation Method Artículo de revista

En: Applied Sciences, vol. 13, no 11460, 2023.

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García-Mendívil, L; Pérez-Zabalza, M; Duwé, S; Ordovás, L; Pueyo, E

Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy Artículo de revista

En: Star Protocols, vol. 4, no 102730, 2023.

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Conferencias

Pérez-Martínez, A; López-Andrés, C; Pastor-Oliver, C; Pueyo, E; Oliván-Viguera, A

Chronic myocardial infarction attenuates transmural heterogeneities and alters the response to endothelin and β-adrenergic stimulation in porcine ventricles Conferencia

Cross-Talk of cell in the Heart: Novel Mechanisms of Disease and Arrhythmias meeting, Liverpool, United Kingdom, 2023.

Enlaces | BibTeX

Pérez-Martínez, A; Rosales, R M; Pastor, C; Oliván-Viguera, A; Pueyo, E

Cold storage of cardiac slices better preserve the native characteristics of cardiac tissue than traditional culture methods Conferencia

47th EWGCCE Annual meeting of the ESC Working Group on Cardiac Cellular Electrophysiology, Copenhagen, Dennmark, 2023.

Enlaces | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; García-Mendivil, L; Vaca-Nuñez, A S; Bellido-Morales, J A; Sorribas-Berjón, J F; Matamala-Adell, M; Vázquez-Sancho, M; Fañanás-Mastral, J; Vallejo-Gil, J M; Ballester-Cuenca, C; Pueyo, E

Eletrophysiologycal and immunohistological evaluation of SK channels from human ventricles: differential functional expression in valvular disease Conferencia

47th EWGCCE Annual meeting of the ESC Working Group on Cardiac Cellular Electrophysiology, Copenhagen, Dennmark, 2023.

Enlaces | BibTeX

Sales-Bellés, C; Melero, J; Ramos, J; Mincholé, A; Pueyo, E

Análisis frecuencial del complejo QRS del electrocardiograma para la caracterización de la estimulación con marcapasos Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Garrido-Huéscar, E; Vandeweyer, L; García-Mendivil, L; Hernández-Bellido, N; Pueyo, E; de Vos, W H; Ordovás, L

Cardiomiocitos derivados de células pluripotentes inducidas (hiPSC-CM) con progerina inducible para estudiar envejecimiento cardiaco Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Pérez-Martínez, A; Pueyo, E; Oliván-Viguera, A

Evaluación electrofisiológica e immunohistológica de canales SK en ventrículo humano: expresión funcional en patología valvular Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Hernández-Bellido, N; Ramos-Marquès, E; Hernández-Vicente, A; García-Mendivil, L; Santander-Badules, H; Mercanti, G; Garrido-Huéscar, E; Garatachea, N; Köhler, R; Pueyo, E; Ordovás, L

microRNAs en envejecimiento cardiaco humano: dianas terapéuticas y biomarcadores Conferencia

XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2023.

Enlaces | BibTeX

Romagnoli, S; Pérez, C; Burattini, L; Pueyo, E; Morettini, M; Sbrollini, A; Martínez, J P; Laguna, P

Model-based Estimators of QT Series Time Delay in Following Heart-Rate Changes Conferencia

45nd Annual International Conference of the IEEE EMBS, Sydney, Australia, 2023.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Abdollahpur, M; Sandberg, F; Laguna, P; Pueyo, E

Dependence of Atrial Fibrillatory Rate Variations Induced by Head-Up/Down Tilt-Test on Autonomic Action Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Noguero-Soler, I; Revilla, P; Ramos, J; Pueyo, E; Mincholé, A

ECG Morphology-Based Markers for Risk Stratification in Hypertrophic Cardiomyopathy Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

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Rodríguez-Carbó, J; Mincholé, A; Pueyo, E

ECG-based Characterization of the Extent, Severity and Spatial Location of Acute Ischemia in Patients with and without Prior Myocardial Infarction Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Pérez, C; Pueyo, E; Martínez, J P; Sörnmo, L; Laguna, P

Evaluation of a QT Adaptation Time Estimator for ECG Exercise Stress Test in Controlled Simulation Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Rosales, R; Mountris, K; Doblaré, M; Mazo, M; Pueyo, E

In Silico Assessment of Arrhythmic Risk in Infarcted Ventricles Engrafted with Engineered Heart Tissues Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Sales-Bellés, C; Mincholé, A; Melero, J; Cabrera-Ramos, M; Montilla-Padilla, I; Sorinas, L; Julián, I; Pueyo, E; Ramos, J

Left Bundle Branch Area Pacing Generates More Physiological Ventricular Activation Sequences than Right Ventricular Pacing Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

García-Mendívil, L; Pérez, M; Rosales, R; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Ordovás, L; Pueyo, E

Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Bueno-Palomeque, F L; Mountris, K; Ortigosa, N; Bailón, R; Bijnens, B; Crispi, F; Pueyo, E; Mincholé, A; Laguna, P

QRS Width and T-peak to T-end Interval Are Prolonged in Preadolescents with Severe Intrauterine Growth Restriction at Birth When Compared to Controls Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Palacios, S; Smisek, R; Curila, K; Nguyen, U C; Prinzen, F; Halamek, J; Plesinger, F; Jurak, P; Pueyo, E; Martínez, J P

Spatial Dispersion of Activation and Repolarization Times Associated with Different Cardiac Pacing Modes Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Enlaces | BibTeX

Bueno, J M; Martínez-Ojeda, R M; Asensio, M C; García-Mendívil, L; Pérez-Zabalza, M; Ordovás, L; Pueyo, E

Age-related Changes in Tissue Structure of the Heart Left Ventricle Assessed with Multiphoton Microscopy Conferencia

Optica Biophotonics Congress: Optics in the Life Sciences, Vancouver (Canada), 2023.

BibTeX

Hernández-Bellido, N; Ramos-Marquès, E; Hernández-Vicente, A; García-Mendívil, L; Santanter-Badules, H; Mercanti, G; Garrido-Huéscar, E; Garatachea, N; Kohler, R; Pueyo, E; Ordovás, L

microRNAs in human cardiac aging: therapeutic targets and biomarkers Conferencia

I Congreso de Estudiantes de Doctorado Iberus Connect (CEDIC), Zaragoza (Spain), 2023.

BibTeX

Garrido-Huéscar, E; Vandeweyer, L; García-Mendívil, L; Hernández-Bellido, N; Pueyo, E; Vos, W H De; Ordovás, L

A progerin-inducible human Induced Pluripotent Stem Cell line to study cardiac cell aging Conferencia

4th International Meeting on Laminopathies, Madrid (Spain), 2023.

BibTeX

310 registros « 1 de 11 »