Faculty Member
Call: +34 976 76 2963
Email: epueyo@unizar.es
Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)
ABOUT ME
Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.
After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.
In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.
Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.
PUBLICATIONS
2008
Conferences
Pueyo, E; Laguna, P; Rodríguez, B
Mechanisms of ventricular heart rate adaptation as an indicator of arrhythmic risk Conference
Heart Rhythm, 29th Annual Scientific Sessions, 2008.
@conference{Pueyo_c008,
title = {Mechanisms of ventricular heart rate adaptation as an indicator of arrhythmic risk},
author = {E Pueyo and P Laguna and B Rodríguez},
url = {https://drive.google.com/file/d/1nPwG7JF0PJSeMT-lS_R-XmvQLtOVYvuU/view},
year = {2008},
date = {2008-01-01},
booktitle = {Heart Rhythm, 29th Annual Scientific Sessions},
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pubstate = {published},
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2007
Journal Articles
Pueyo, E; Laciar, E; Anzuola, E; Laguna, P; Jané, R
QRS slopes for assessment of myocardial damage in chronic chagasic patients Journal Article
In: Journal of Physics: Conference Series, vol. 90, no. 012077, 2007.
@article{Pueyo07,
title = {QRS slopes for assessment of myocardial damage in chronic chagasic patients},
author = {E Pueyo and E Laciar and E Anzuola and P Laguna and R Jané},
url = {https://drive.google.com/file/d/1bNtyLwNZAnMeitOVEhr4OmbyTlOZaILL/view},
doi = {10.1088/1742-6596/90/1/012077},
year = {2007},
date = {2007-01-01},
journal = {Journal of Physics: Conference Series},
volume = {90},
number = {012077},
keywords = {},
pubstate = {published},
tppubtype = {article}
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Conferences
Pueyo, E; Anzuola, E; Laciar, E; Laguna, P; Jané, R
Assessment of Myocardial Damage in Chronic Chagasic Patients using QRS Slopes Conference
Computers in Cardiology, 2007.
@conference{Pueyo_c207,
title = {Assessment of Myocardial Damage in Chronic Chagasic Patients using QRS Slopes},
author = {E Pueyo and E Anzuola and E Laciar and P Laguna and R Jané},
url = {https://drive.google.com/file/d/1gDIqBp7xJDac-r4OkwsK_plH_3k4WyEM/view},
year = {2007},
date = {2007-01-01},
booktitle = {Computers in Cardiology},
pages = {725-728},
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pubstate = {published},
tppubtype = {conference}
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Simón, F; Laguna, P; Pueyo, E
Study of the Dynamic Relationship between T Wave Morphology and Heart Rate during Ischemia Conference
Computers in Cardiology, 2007.
@conference{Simon_c207,
title = {Study of the Dynamic Relationship between T Wave Morphology and Heart Rate during Ischemia},
author = {F Simón and P Laguna and E Pueyo},
url = {https://drive.google.com/file/d/141S56ySUd4VBKOdG31ZgrPSL92ACwZHG/view},
year = {2007},
date = {2007-01-01},
booktitle = {Computers in Cardiology},
pages = {297-300},
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pubstate = {published},
tppubtype = {conference}
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Pueyo, E; Malik, M; Laguna, P
Dynamic Repolarization Assessment and Arrhythmic Risk Stratification Conference
11th Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007, 2007.
@conference{Pueyo_c007,
title = {Dynamic Repolarization Assessment and Arrhythmic Risk Stratification},
author = {E Pueyo and M Malik and P Laguna},
url = {https://drive.google.com/file/d/1Fr9jsbNlNECYBTpxN0qrz80gxb22AjBH/view},
doi = {10.1007/978-3-540-73044-6. 2007},
year = {2007},
date = {2007-01-01},
booktitle = {11th Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007},
pages = {74-77},
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pubstate = {published},
tppubtype = {conference}
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Pueyo, E; Laciar, E; Anzuola, E; Laguna, P; Jané, R
Pendientes del QRS para la evaluación del daño miocárdico en pacientes chagásicos crónicos Conference
Comunicaciones del XVI Congreso Sociedad Argentina de Bioingeniería, San Juan, Argentina, 2007.
@conference{Pueyo_c007b,
title = {Pendientes del QRS para la evaluación del daño miocárdico en pacientes chagásicos crónicos},
author = {E Pueyo and E Laciar and E Anzuola and P Laguna and R Jané},
url = {https://drive.google.com/file/d/1oHJ3aGO00EVrwcZn78uqTikn1Onmt5wn/view},
year = {2007},
date = {2007-01-01},
booktitle = {Comunicaciones del XVI Congreso Sociedad Argentina de Bioingeniería},
pages = {543-546},
address = {San Juan, Argentina},
keywords = {},
pubstate = {published},
tppubtype = {conference}
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2006
Journal Articles
Almeida, R; Gouveia, S; Rocha, A P; Pueyo, E; Martínez, J P; Laguna, P
QT variability and HRV interactions in ECG: Quantification and Reliability Journal Article
In: IEEE Trans. on Biomedical Engineering, vol. 53, no. 7, pp. 1317-1329, 2006.
@article{Almeida06,
title = {QT variability and HRV interactions in ECG: Quantification and Reliability},
author = {R Almeida and S Gouveia and A P Rocha and E Pueyo and J P Martínez and P Laguna},
url = {https://drive.google.com/file/d/1zsp2zMRtkW2sl65Uq6jyLcQmKRxAYIh6/view},
doi = {10.1109/TBME.2006.873682},
year = {2006},
date = {2006-01-01},
journal = {IEEE Trans. on Biomedical Engineering},
volume = {53},
number = {7},
pages = {1317-1329},
keywords = {},
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PhD Theses
Pueyo, E
2006.
@phdthesis{Pueyo_thesis06,
title = {Detección de heterogeneidades en la depolarización y repolarización cardiacas a partir del electrocardiograma como mejora en la predicción del riesgo frente a arritmias},
author = {E Pueyo},
url = {https://drive.google.com/file/d/1iHBaCG1w4szk_YP8z-8hSYBdXjIiHu3H/view},
year = {2006},
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2005
Conferences
Pueyo, E; Arcineaga, A; Laguna, P
XXXII Ann. Conf. Computers in Cardiology, Lyon, 2005.
@conference{Pueyo_c105,
title = {High-Frequency Signature of the QRS Complex across Ischemia in PTCA Recordings Quantified by the Downward Slope of the QRS Complex},
author = {E Pueyo and A Arcineaga and P Laguna},
url = {https://drive.google.com/file/d/1ae38UyCKiCxGhyCJjGH6jA8lNxYtS4hj/view},
year = {2005},
date = {2005-01-01},
booktitle = {XXXII Ann. Conf. Computers in Cardiology},
pages = {659-662},
address = {Lyon},
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Pueyo, E; Malik, M; Laguna, P
Beat-to-beat Adaptation of QT Interval to Heart Rate Conference
27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. (EMBS05), Shanghai, 2005.
@conference{Pueyo_c405,
title = {Beat-to-beat Adaptation of QT Interval to Heart Rate},
author = {E Pueyo and M Malik and P Laguna},
url = {https://drive.google.com/file/d/1zw_I0xCM6csYxvvZrp89Ltn_a795D8Gg/view},
year = {2005},
date = {2005-01-01},
booktitle = {27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. (EMBS05)},
address = {Shanghai},
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pubstate = {published},
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2004
Journal Articles
Pueyo, E; Smetana, P; Caminal, P; Luna, A Bayés; Malik, M; Laguna, P
In: IEEE Trans. on Biomedical Engineering, vol. 51, no. 9, pp. 1511-1520, 2004.
@article{Pueyo04,
title = {Characterization of QT Interval Adaptation to RR Interval Changes and Its Use as a Risk-Stratifier of Arrhythmic Mortality in Amiodarone-Treated Survivors of Acute Myocardial Infarction},
author = {E Pueyo and P Smetana and P Caminal and A Bayés Luna and M Malik and P Laguna},
url = {https://drive.google.com/file/d/1u3u7D0W-4C_rzg3j9MvLVBrnfcJM1Rd8/view},
doi = {10.1109/TBME.2004.828050},
year = {2004},
date = {2004-01-01},
journal = {IEEE Trans. on Biomedical Engineering},
volume = {51},
number = {9},
pages = {1511-1520},
keywords = {},
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Pueyo, E; García, J; Wagner, G; Bailón, R; Sörnmo, L; Laguna, P
Time course of ECG Depolarization and Repolarization changes during Ischemia in PTCA recordings Journal Article
In: Methods Inf. Med., vol. 43, pp. 43-46, 2004.
@article{Pueyo04b,
title = {Time course of ECG Depolarization and Repolarization changes during Ischemia in PTCA recordings},
author = {E Pueyo and J García and G Wagner and R Bailón and L Sörnmo and P Laguna},
url = {https://drive.google.com/file/d/1kDO4z8ZXsKKYoMjpuRyB1hK8ru4e0GIl/view},
year = {2004},
date = {2004-01-01},
journal = {Methods Inf. Med.},
volume = {43},
pages = {43-46},
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Pueyo, E; Smetana, P; Laguna, P; Malik, M
Assessment of individual QT/RR relationship and hysteresis in post-infarction patients Journal Article
In: Italian Heart Journal, vol. 5, no. 1, pp. 165S-168S, 2004.
@article{Pueyo04c,
title = {Assessment of individual QT/RR relationship and hysteresis in post-infarction patients},
author = {E Pueyo and P Smetana and P Laguna and M Malik},
url = {https://drive.google.com/file/d/1te2wdoxRbP5eKZxGbKw2v6sYNw1yAyrI/view},
year = {2004},
date = {2004-01-01},
urldate = {2004-01-01},
booktitle = {Italian Heart Journal},
journal = {Italian Heart Journal},
volume = {5},
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Smetana, P; Pueyo, E; Hnatkova, K; Batchvarov, V; Laguna, P; Malik, M
In: Journal of Cardiovascular Electrophysiology, vol. 15, no. 10, pp. 1147-1154, 2004.
@article{Smetana04,
title = {Individual patterns of dynamic QT/RR relationship in survivors of acute myocardial infarction and their relationship to antiarrhythmic efficacy of amiodarone},
author = {P Smetana and E Pueyo and K Hnatkova and V Batchvarov and P Laguna and M Malik},
url = {https://drive.google.com/file/d/18-7Y9xqCB1ZB1QRzX5F5eqLDW7uhYXO7/view},
doi = {10.1046/j.1540-8167.2004.04076.x},
year = {2004},
date = {2004-01-01},
journal = {Journal of Cardiovascular Electrophysiology},
volume = {15},
number = {10},
pages = {1147-1154},
keywords = {},
pubstate = {published},
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Conferences
Almeida, R; Pueyo, E; Martínez, J P; Rocha, A P; Laguna, P
XXXI International Conference on Computers in Cardiology, Chicago, 2004.
@conference{Almeida_c104,
title = {Quantification of the QT Variability Related to HRV: Robustness Study Facing Automat Delineation and Noise on the ECG},
author = {R Almeida and E Pueyo and J P Martínez and A P Rocha and P Laguna},
url = {https://drive.google.com/file/d/10uIeQnTvjmG0mgev2m_-vhNnGG0J41xh/view},
year = {2004},
date = {2004-01-01},
booktitle = {XXXI International Conference on Computers in Cardiology},
pages = {769-772},
address = {Chicago},
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Almeida, R; Rocha, A P; Pueyo, E; Martínez, J P; Laguna, P
Modelling short term variability interactions in ECG: QT versus RR Conference
COMPSTAT’2004 Symposium, Physica-Verlag Heidelberg New York, Prague, Czech Republic, 2004, ISBN: 3-7908-1554-3.
@conference{Almeida_c304,
title = {Modelling short term variability interactions in ECG: QT versus RR},
author = {R Almeida and A P Rocha and E Pueyo and J P Martínez and P Laguna},
url = {https://drive.google.com/file/d/1CDdCcsQrXqoMFcceo2CRi7jsXWb1hirK/view},
isbn = {3-7908-1554-3},
year = {2004},
date = {2004-01-01},
booktitle = {COMPSTAT'2004 Symposium},
pages = {597-604},
publisher = {Physica-Verlag Heidelberg New York},
address = {Prague, Czech Republic},
keywords = {},
pubstate = {published},
tppubtype = {conference}
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2003
Journal Articles
Pueyo, E; Smetana, P; Laguna, P; Malik, M
Estimation of the QT/RR hysteresis lag Journal Article
In: Journal of Electrocardiology, Supplement, vol. 36, no. 4, pp. 187-190, 2003.
@article{Pueyo03,
title = {Estimation of the QT/RR hysteresis lag},
author = {E Pueyo and P Smetana and P Laguna and M Malik},
url = {https://drive.google.com/file/d/1GzdAy0zgIaXwKcD5YkB_JPmT0N95b-UE/view},
doi = {10.1016/j.jelectrocard.2003.09.056},
year = {2003},
date = {2003-01-01},
journal = {Journal of Electrocardiology, Supplement},
volume = {36},
number = {4},
pages = {187-190},
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Smetana, P; Pueyo, E; Hnatkova, K; Batchvarov, V; Camm, A J; Malik, M
Effect of amiodarone on the descending limb of the T wave Journal Article
In: American Journal of Cardiology, vol. 92, pp. 742-746, 2003.
@article{Smetana03,
title = {Effect of amiodarone on the descending limb of the T wave},
author = {P Smetana and E Pueyo and K Hnatkova and V Batchvarov and A J Camm and M Malik},
url = {https://drive.google.com/file/d/1io6JMguaEdb0PIxmEgSbHKRXuc2SHRu3/view},
doi = {10.1016/S0002-9149(03)00845-2},
year = {2003},
date = {2003-01-01},
journal = {American Journal of Cardiology},
volume = {92},
pages = {742-746},
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Conferences
Almeida, R; Pueyo, E; Martínez, J P; Rocha, A P; Laguna, P; Olmos, S
Quantification of short term QT variability versus heeart rate variability Conference
7th Portuguese Conference on Biomedical Engineering (BioEng’2003), Lisboa, 2003.
@conference{Almeida_c003,
title = {Quantification of short term QT variability versus heeart rate variability},
author = {R Almeida and E Pueyo and J P Martínez and A P Rocha and P Laguna and S Olmos},
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Pueyo, E; Smetana, P; Malik, M; Laguna, P
XXX International Conference on Computers in Cardiology, Tesalonica, 2003.
@conference{Pueyo_c103,
title = {Evaluation of QT Interval Response to Marked RR Interval Changes Selected Automatically in Ambulatory Recordings},
author = {E Pueyo and P Smetana and M Malik and P Laguna},
url = {https://drive.google.com/file/d/1Q5pUX67NIoKm7AEkGTUzZKihdwj4AShw/view},
year = {2003},
date = {2003-01-01},
booktitle = {XXX International Conference on Computers in Cardiology},
pages = {157-160},
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Almeida, R; Pueyo, E; Martínez, J P; Rocha, A P; Olmos, S; Laguna, P
XXX International Conference on Computers in Cardiology, Tesalonica, 2003.
@conference{Almeida_c103,
title = {A Parametric Model Approach for Quantification of Short Term QT Variability Uncorrelated with Heart Rate Variability},
author = {R Almeida and E Pueyo and J P Martínez and A P Rocha and S Olmos and P Laguna},
url = {https://drive.google.com/file/d/1lbu55DxvtfHgYxe9grcnPtuWS9a5q-H6/view},
year = {2003},
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booktitle = {XXX International Conference on Computers in Cardiology},
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2002
Conferences
Pueyo, E; García, J; Wagner, G; Bailón, R; Sörnmo, L; Laguna, P
Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings Conference
4th Biosignal interpretation international workshop, IEEE Computer Society, Como, 2002.
@conference{Pueyo_c002,
title = {Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings},
author = {E Pueyo and J García and G Wagner and R Bailón and L Sörnmo and P Laguna},
url = {https://drive.google.com/file/d/1pbpd0JXQGbXa5lxEgIQo7PdgtmtRcM4K/view},
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booktitle = {4th Biosignal interpretation international workshop, IEEE Computer Society},
pages = {115-118},
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Pueyo, E; Smetana, P; Knatkoval, H; Malik, M; Laguna, P
Tiempo de adaptación del QT a cambios en el RR, relación con el riesgo de muerte arrítmica Conference
XX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB’02), Zaragoza, 2002.
@conference{Pueyo_c102,
title = {Tiempo de adaptación del QT a cambios en el RR, relación con el riesgo de muerte arrítmica},
author = {E Pueyo and P Smetana and H Knatkoval and M Malik and P Laguna},
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Pueyo, E; Smetana, P; Hnatkoval, K; Laguna, P; Malik, M
XXIX International Conference on Computers in Cardiology, Memphis, 2002.
@conference{Pueyo_202,
title = {Time for QT Adaptation to RR Changes and Relation to Arrhythmic Mortality Reduction in Amiodarone-treated Patients},
author = {E Pueyo and P Smetana and K Hnatkoval and P Laguna and M Malik},
url = {https://drive.google.com/file/d/10TsDbpnxT2Tec1oG2FQprwoa4eVzsWGg/view},
year = {2002},
date = {2002-01-01},
booktitle = {XXIX International Conference on Computers in Cardiology},
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