Faculty Member

Call: +34 976 76 2963

Email: epueyo@unizar.es

Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)

ABOUT ME

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

PUBLICATIONS
300 registros « 3 de 10 »

2022

Conferencias

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new computational models to evaluate age-related drugs cardiotoxicity Conferencia

XI Jornada de Jóvenes Investigadores del Instituto de Investigación en Ingeniería de Aragón (I3A), Zaragoza, Spain, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new human models to determine age-related cardiotoxicity of drugs Conferencia

I ipIBA Day, Zaragoza, Spain, 2022.

BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new human models to determine age-related cardiotoxicity of drugs Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Budapest, Hungría, 2022.

BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Human cardiac models for investigation of age-related cardiotoxic effects of drug compounds Conferencia

XV CIBER-BBN Annual Conference, Valencia, Spain, 2022.

BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA Conferencia

XI Jornada de Jóvenes Investigadores, Zaragoza, Spain, 2022.

Enlaces | BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Towards advanced cardiac miRNA therapies through DNA-based nanostructures Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Budapest, Hungría, 2022.

Enlaces | BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA Conferencia

I iPIBA Day, Zaragoza, Spain, 2022.

BibTeX

Velarte, A; Otín, A; Guimera, A; Pueyo, E; Villa, R

Improving Signal Stability in a Multi-Electrode Array (MEA) System for Cardiac Biopsies Conferencia

Proceedings of the 37th Conference on Design of Circuits and Integrated Systems, Pamplona, Spain, 2022.

Enlaces | BibTeX

Velarte, A; Otín, A; Pueyo, E

Análisis y modelado de la impedancia de una matriz de microelectrodos (MEA) fabricados en oro mediante platino negro Conferencia

XI Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2022.

Enlaces | BibTeX

2021

Artículos de revista

Hernández-Vicente, A; Hernando, D; Marín-Puyalto, J; Vicente-Rodríguez, G; Garatachea, N; Pueyo, E; Bailón, R

Validity of the Polar H7 Heart Rate Sensor for Heart Rate Variability Analysis during Exercise in Different Age, Body Composition and Fitness Level Groups Artículo de revista

En: Sensors, vol. 21, no 902, 2021.

Enlaces | BibTeX

Segovia-Roldán, M; Diez, E R; Pueyo, E

Melatonin to rescue the aged heart: antiarrhythmic and antioxidant benefits. Oxidative Medicine and Cellular Longevity Artículo de revista

En: Oxidative Medicine and Cellular Longevity, vol. ID 8876792, pp. 1-18, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Nonlinear T-wave Time Warping-based Sensing Model for Non-invasive Personalized Blood Potassium Monitoring in Hemodialysis Patients Artículo de revista

En: Sensors, vol. 21, no 2710, 2021.

Enlaces | BibTeX

Mountris, K A; Pueyo, E

A dual adaptive explicit time integration algorithm for efficiently solving the cardiac monodomain equation Artículo de revista

En: Int J Numer Meth Biomed Engng, vol. e3461, 2021.

Enlaces | BibTeX

Taggart, P; Pueyo, E; Duijvenboden, S V.; Porter, B; Bishop, M; Sampedro-Puente, D A; Orini, M; Hanson, B; Rinaldi, C A; Gill, J S; Lambiase, P

Emerging evidence for a mechanistic link between low-frequency oscillation of ventricular repolarization measured from the electrocardiogram T-wave vector and arrhythmia Artículo de revista

En: Europace, vol. euab009, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

ECG-based Monitoring of Blood Potassium Concentration: Periodic versus Principal Componentas Lead Transformation for Biomarker Robustness Artículo de revista

En: Biomedical Signal Processing and Control, vol. 68, no 102719, pp. 1-11, 2021.

Enlaces | BibTeX

Castillo, M González; Hernando, D; Orini, M; Laguna, P; Viik, J; Bailón, R; Pueyo, E

QT variability unrelated to RR variability during stress testing for identification of coronary artery disease Artículo de revista

En: Phil. Trans. R. Soc. A., vol. 379: 20200261, 2021.

Enlaces | BibTeX

Celotto, C; Sanchez, C; Mountris, K A; Laguna, P; Pueyo, E

Location of Parasympathetic Innervation Regions from Electrograms to Guide Atrial Fibrillation Ablation Therapy: An In Silico Modeling Study Artículo de revista

En: Frontiers in Physiology, vol. 12, no 674197, 2021.

Enlaces | BibTeX

Barrio, R; Martínez, M A; Pueyo, E; Serrano, S

Dynamical analysis of early afterdepolarization patterns in a biophysically-detailed cardiac model Artículo de revista

En: Chaos, vol. 31, no 073137, pp. 1-20, 2021.

Enlaces | BibTeX

Ramos-Marquès, E; García-Mendívil, L; Pérez-Zabalza, M; Santander-Badules, H; Srinivasan, S; Oliveros, J C; Torres-Pérez, R; Cebollada, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Jiménez-Navarro, M; Villaescusa, J M; Garrido-Huéscar, E; Segovia-Roldán, M; Oliván-Viguera, A; Gómez-González, C; Muñiz, G; Diez, E; Ordovás, L; Pueyo, E

Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution Artículo de revista

En: Aging Cell, vol. 00:e13383, pp. 1-16, 2021.

Enlaces | BibTeX

Hernández-Vicente, A; Hernando, D; Vicente-Rodríguez, G; Bailón, R; Garatachea, N; Pueyo, E

ECG ventricular repolarization dynamics during exercise: temporal profile, relation to heart rate variability and effects of age and physical health Artículo de revista

En: International Journal of Environmental Research and Public Health, vol. 18, no 9497, 2021.

Enlaces | BibTeX

Palacios, S; Cygankiewicz, I; Luna, A Bayés; Pueyo, E; Martínez, J P

Periodic Repolarization Dynamics as Predictor of Risk for Sudden Cardiac Death in Chronic Heart Failure Patients Artículo de revista

En: Scientific Reports, vol. 11:20546, 2021.

Enlaces | BibTeX

Bukhari, H A; Palmieri, F; Ramirez, J; Laguna, P; Ruiz, J E; Ferreira, D; Potse, M; Sánchez, C; Pueyo, E

Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate Artículo de revista

En: IEEE Trans Biomed Eng, vol. 68, no 8, pp. 2467-2478, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ferreira, D; Ruiz, J E; Bergasa, B; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Monitoring Blood Potassium Concentration in Hemodialysis Patients by Quantifying T-wave Morphology Dynamics Artículo de revista

En: Scientific reports, vol. 11, no 3883, 2021.

Enlaces | BibTeX

Conferencias

Palacios, S; Cygankiewicz, I; Bayés-de-Luna, A; Martínez, J P; Pueyo, E

Estudio de la dinámica periódica de la repolarización para la predicción de muerte súbita en pacientes con insuficiencia cardíaca crónica Conferencia

I Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernandez, Elche 2021.

Enlaces | BibTeX

Gómez, M; Carro, J; Pueyo, E; Monasterio, V

Modificación de un modelo de miocito ventricular humano para representar el papel de los canales SK en insuficiencia cardiaca Conferencia

XXXIX Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Madrid, España, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Pueyo, E; Martínez, J P; Laguna, P; Ramírez, J

Time-Warping” ponderado sobre la onda T para Reducir el Impacto de Errores de Delineación: Implicaciones Clínicas Conferencia

XXXIX Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Madrid, España, 2021.

Enlaces | BibTeX

Pérez-Martínez, C; Martín-Yebra, A; Viik, J; Martínez, J P; Pueyo, E; Laguna, P

Spatial ECG filtering by Periodic component analysis for improved QT delineation in stress test recordings Conferencia

55th Asilomar Conference on Signals, Systems and Computers, 2021.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Laguna, P

Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings Conferencia

International Society for Computerized Electrocardiology -ISCE-2020, 2021.

BibTeX

Bukhari, H A; Laguna, P; Potse, M; Sánchez, C; Pueyo, E

QRS Slopes for Potassium and Calcium Monitoring in End-Stage Renal Disease Patients Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Pueyo, E; Martínez, J P; Laguna, P; Ramírez, J

Weighted Time Warping T-wave Analysis Robust to Delineation Errors: Clinical Implications Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

300 registros « 3 de 10 »