Faculty Member

Call: +34 976 76 2963

Email: epueyo@unizar.es

Address: Mariano Esquillor s/n, 50018, Zaragoza (Spain) (Spain)

ABOUT ME

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

PUBLICATIONS
300 registros « 5 de 10 »

2020

Conferencias

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Viik, J; Laguna, P

Characterization of Impaired Ventricular Repolarization by Quantification of QT Delayed Response to Heart Rate Changes in Stress Test Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

In Silico Characterization of Repolarization Duration and Variability in the Long QT1 Syndrome Under β-Adrenergic Stimulation Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Srinivasan, S; Bukhari, H A; Laguna, P; Sánchez, C; Pueyo, E

Analysis of T Wave Nonlinear Dynamics for Serum Potassium Monitoring in End-Stage Renal Disease Patients Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Mountris, K A; Abdollahpur, M; Sandberg, F; Laguna, P; Pueyo, E

Relationship Between Atrial Oscillatory Acetylcholine Release Pattern and f-wave Frequency Modulation: a Computational and Experimental Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Bueno-Palomeque, F L; Mountris, K A; Minchole, A; Ortigosa, N; Pueyo, E; Laguna, P

Changes in QRS and T-wave Loops Subsequent to an Increase in Left Ventricle Globularity as in Intrauterine Growth Restriction: a Simulation Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Laguna, P; Martínez, J P; Ramírez, J

Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Palacios, S; Martínez, J P; Pueyo, E

Sudden Cardiac Death Prediction in Chronic Heart Failure Patients by Periodic Repolarization Dynamics Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Pérez-Zabalza, M; Diez, E R; Rhyins, J; Mountris, K A; Segovia-Roldán, M; Oliván-Viguera, A; Pueyo, E

Improved methods for processing optical mapping signals from human left ventricular tissues at baseline and following adrenergic stimulation Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Mountris, K A; Pueyo, E

Next-generation in-silico Cardiac Electrophysiology through Immersed Grid Meshfree Modelling Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX

Palacios, S; Cygankiewicz, I; Bayés-de-Luna, A; Martínez, J P; Pueyo, E

Predicción de muerte súbita en pacientes con insuficiencia cardíaca crónica mediante el estudio de la dinámica periódica de la repolarización Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Laguna, P; Martínez, J P; Ramírez, J

Monitorización en diálisis de la Concentración de Potasio en Sangre mediante los cambios en la morfología multi-lead de la onda T: Comparación Entre usar la transformación en Componentes Periódicas y Principales Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

Caracterización in silico de la duración de la repolarización y su variabilidad en el síndrome de QT Largo Tipo1 bajo estimulación β adrenérgica Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Viik, J; Laguna, P

Retardo entre QT y RR en registros de prueba de esfuerzo como indicador de la heterogeneidad de la repolarización ventricular Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Capítulos de libros

Prado, N J; Segovia-Roldan, M; Diez, E R; Pueyo, E

Melatonin for a Healthy Heart Rhythm Capítulo de libro

En: IntechOpen, 2020.

Enlaces | BibTeX

2019

Artículos de revista

Sampedro-Puente, D A; Fernandez-Bes, J; Virág, L; Varró, A; Pueyo, E

Data-driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-beat Variability Artículo de revista

En: IEEE Journal of Biomedical and Health Informatics, 2019.

Enlaces | BibTeX

Mountris, K A; Bourantas, G C; Millán, D; Joldes, G R; Miller, K; Pueyo, E; Wittek, A

Cell‐based maximum entropy approximants for three‐dimensional domains: Application in large strain elastodynamics using the meshless total Lagrangian explicit dynamics method Artículo de revista

En: Int J Numer Methods Eng, pp. 1-15, 2019.

Enlaces | BibTeX

Duijvenboden, S; Porter, B; Pueyo, E; Sampedro-Puente, D A; Fernandez-Bes, J; Sidhu, B; Gould, J; Orini, M; Bishop, M; Hanson, B; Lambiase, P; Razavi, R; Rinaldi, C A; Gill, J S; Taggart, P

Complex interaction between low-frequency APD oscillations and beat-to-beat APD variability in humans is governed by the sympathetic nervous system Artículo de revista

En: Front. Physiol., 2019.

Enlaces | BibTeX

Ramírez, J; Duijvenboden, S Van; Aung, N; Laguna, P; Pueyo, E; Tinker, A; Lambiase, P; Orini, M; Munroe, P

Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics Artículo de revista

En: Circulation: Arrhythmia and Electrophysiology, 2019.

Enlaces | BibTeX

Sampedro-Puente, D A; Fernandez-Bes, J; Porter, B; Duijvenboden, S; Taggart, P; Pueyo, E

Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat variability of celullar ventricular repolarization in response to sympathetic stimulation: Implications for arrhythmogenesis Artículo de revista

En: Frontiers in Physiology, vol. 10, no 916, pp. 1-18, 2019.

Enlaces | BibTeX

Palacios, S; Caiani, E G; Landreani, F; Martínez, J P; Pueyo, E

Long-term microgravity exposure increases ECG repolarization instability manifested by low-frequency oscillations of T-wave vector Artículo de revista

En: Front. Physiol., vol. 10, no 1510, 2019.

Enlaces | BibTeX

Valero, M S; Ramón-Gimenez, M; Lozano-Gerona, J; Delgado-Wicke, P; Calmarza, P; Olivan-Viguera, A; López, V; Garcia-Otín, Á L; Valero, S; Pueyo, E; Hamilton, K L; Miura, H; Köhler, R

Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility Artículo de revista

En: International Journal of Molecular Sciences, vol. 20, no 1193, 2019.

Enlaces | BibTeX

Conferencias

Bukhari, H A; Palmieri, F; Ferreira, D; Potse, M; Ramírez, J; Laguna, P; Sánchez, C; Pueyo, E

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Serum Potassium Levels Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Laguna, P; Pueyo, E

Calcium-Activated Potassium Channels Inhibition in Autonomically Stimulated Human Atrial Myocytes Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Bergasa, B; Ferreira, D; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ferreira, D; Ruiz, J E; Bergasa, B; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Estudio de los Cambios en la Morfología de las Ondas T como Sustituto de la Concentración de Potasio en Sangre en Pacientes de Hemodiálisis Conferencia

XXXVII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Santander, España, 2019.

Enlaces | BibTeX

Monasterio, V; Pueyo, E; Rodríguez, J F; Carro, J

Influence of the Stimulation Current on the Differences between Cell and Tissue Electrophysiological Simulations Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Palacios, S; Caiani, E; Pueyo, E; Martínez, J P

Response of Ventricular Repolarization to Simulated Microgravity Measured by Periodic Repolarization Dynamics Using Phase-Rectified Signal Averaging Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Mountris, K A; Sánchez, C; Pueyo, E

A Novel Paradigm for in Silico Simulation of Cardiac Electrophysiology through the Mixed Collocation Meshless Petrov-Galerkin Method Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

Enlaces | BibTeX

Pueyo, E

Combined Experimental and Computational Research into Cardiac-Neural Interactions and Arrhythmias. Invited talk Conferencia

41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Berlin, Germany, 2019.

BibTeX

Ramos, E; García, L; Oliveros, J C; Torres, R; López, A; Oliván, A; Vallejo, J M; Fresneda, P C; Fañanás, J; Matamala, M; Sorribas, F; Vázquez, M; Ballester, C; Ordovás, L; Pueyo, E

The role of microRNAs in age-related remodeling of the human left ventricle Conferencia

European Society of Cardiology (ESC), vol. Poster, 2019.

BibTeX

300 registros « 5 de 10 »