Address

Mariano Esquillor s/n, 50018, Zaragoza (Spain)

Contact Information

Call: +34 976 76 2963

Email: epueyo@unizar.es

Esther Pueyo Paules

Faculty Member

Website

http://www.estherpueyo.com

Biography

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

Publications

277 registros « 1 de 6 »

2023

Artículos de revista

Garatachea, N; Pueyo, E; Eijsvogels, T

Prevention of sudden death in sports: a global and multidisciplinary observatory for scientific research and knowledge transfer Artículo de revista

En: Reviews in Cardiovascular Medicine, vol. 24, iss. 1, no. 12, 2023.

Enlaces | BibTeX

Pérez, C; Cebollada, R; Mountris, K A; Martínez, J P; Laguna, P; Pueyo, E

The Role of β-adrenergic Stimulation in QT Interval Adaptation to Heart Rate During Stress Test Artículo de revista

En: Plos One, 2023.

BibTeX

2022

Artículos de revista

Sánchez, F J; Pueyo, E; Diez, E R

Strain echocardiography to predict postoperative atrial fibrillation Artículo de revista

En: Int. J. Mol. Sci., vol. 23, pp. 1355, 2022.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ferreira, D; Pueyo, E; Martínez, J P; Laguna, P; Ramírez, J

Weighted Time Warping Improves T-wave Morphology Markers Clinical Significance Artículo de revista

En: IEEE Trans Biomed Eng, 2022.

Enlaces | BibTeX

Bukhari, H A; Sánchez, C; Ruiz, J E; Potse, M; Laguna, P; Pueyo, E

Monitoring of Serum Potassium and Calcium Levels in End-stage Renal Disease Patients by ECG Depolarization Morphology Analysis Artículo de revista

En: Sensors, vol. 22, no. 2951, 2022.

Enlaces | BibTeX

Albors, C; Lluch, E; Gomez, J F; Cedilnik, N; Mountris, K A; Mansi, T; Khamzin, S; Dokuchaev, A; Solovyova, O; Pueyo, E; Sermesant, M; Sebastian, R; Morales, H G; Camara, O

Meshless electrophysiological modeling of cardiac resynchronization therapy—benchmark analysis with finite-element methods in experimental data Artículo de revista

En: Applied Sciences, vol. 12, no. 6438, 2022.

Enlaces | BibTeX

Pueyo, E

Modelización matemática y simulación computacional de la variabilidad espacio-temporal en la actividad eléctrica cardíaca Artículo de revista

En: Rev. Real Academia de Ciencias, vol. 76, pp. 7-54, 2022, ISSN: 0370-3207.

Enlaces | BibTeX

Bukhari, H A; Sánchez, C; Srinivasan, S; Palmieri, F; Potse, M; Laguna, P; Pueyo, E

Estimation of Potassium Levels in Hemodialysis Patients by T wave Nonlinear Dynamics and Morphology Markers Artículo de revista

En: Computers in Biology and Medicine, In press, 2022.

Enlaces | BibTeX

Montero-Calle, P; Flandes-Iparraguirre, M; Mountris, K; de la Nava, A S; Laita, N; Rosales, R M; Iglesias-García, O; De-Juan-Pardo, E M; Atienza, F; Fernández-Santos, M E; Peña, E; Doblaré, M; Gavira, J J; Fernández-Avilés, F; Prosper, F; Pueyo, E; Vega, M M Mazo

Fabrication of human myocardium using multidimensional modelling of engineered tissues Artículo de revista

En: Biofabrication, 2022.

Enlaces | BibTeX

Hernández-Vicente, A; Marín-Puyalto, J; Pueyo, E; Vicente-Rodríguez, G; Garatachea, N

Physical activity in centenarians beyond cut-point-based accelerometer metrics Artículo de revista

En: International Journal of Environmental Research and Public Health, 2022.

Enlaces | BibTeX

Monasterio, V; Pueyo, E; Rodríguez-Matas, J F; Carro, J

Cardiac cells stimulated with an axial current-like waveform reproduce electrophysiological properties of tissue fibers Artículo de revista

En: Computer Methods and Programs in Biomedicine, 2022.

Enlaces | BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K; Duwé, S; Smisdom, N; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Oliván-Viguera, A; Diez, E; Ordovás, L; Pueyo, E

Analysis of age-related left ventricular collagen remodeling in living donors: implications in arrhythmogenesis Artículo de revista

En: iScience, 2022.

Enlaces | BibTeX

Barrio, R; Martínez, M A; Serrano, S; Pueyo, E

Dynamical mechanism for generation of arrhythmogenic early afterdepolarizations in cardiac myocytes: Insights from in silico electrophysiological models Artículo de revista

En: Physical Review E., vol. 106, no. 024402, 2022.

Enlaces | BibTeX

Mountris, K; Pueyo, E

A meshless fragile points method for rule-based definition of myocardial fiber orientation Artículo de revista

En: Computer Methods and Programs in Biomedicine, vol. 226, no. 107164, 2022.

Enlaces | BibTeX

Mountris, K; Dong, L; Guan, Y; Atluri, S N; Pueyo, E

A meshless fragile points method for the solution of the monodomain model for cardiac electrophysiology simulation Artículo de revista

En: Journal of Computational Science, vol. 65, no. 101880, 2022.

Enlaces | BibTeX

Conferencias

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Assessment and optimization of conduction system pacing for anti-bradycardia pacemaker therapy Conferencia

STAFF-MALT Symposium 2022, Senohraby, Czech Republic, 2022.

BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Duwé, S; Ordovás, L; Pueyo, E

Caracterización del remodelado del colágeno asociado a la edad en el ventrículo izquierdo humano de donantes vivos y sus implicaciones en la generación de arritmias Conferencia

XI Jornada de Jóvenes Investigadores del I3A, 2022.

Enlaces | BibTeX

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres-Pérez, R; Ramos-Marqués, E; Pueyo, E; Ordovás, L

Envejecimiento cardíaco humano: transcriptómica y desarrollo de modelos celulares Conferencia

II Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernández, Elche, 2022.

BibTeX

Sales, C; Pueyo, E; Julián, I; Sorinas, L; Cabrera, M; Ruiz, J R; Ramos, J

Cambios en la despolarización y repolarización producidos por la estimulación de rama izquierda frente a la estimulación convencional Conferencia

Ritmo22, Granada, España, 2022.

BibTeX

Melero, J; Sales, C; Julián, I; Ruiz, J R; Pueyo, E; Ramos, J

Estimulación de rama izquierda frente a estimulación de ventrículo derecho: cambios en la despolarización y en la repolarización Conferencia

Congreso de la Salud Cardiovascular, Palma de Mallorca, España, 2022.

BibTeX

Sales, C; Melero, J; Julián, I; Ramos, J; Mincholé, A; Pueyo, E

Comparación de los efectos de la estimulación cardíaca convencional y la estimulación de rama izquierda sobre la despolarización y repolarización ventricular en el ECG Conferencia

Jornadas de Jóvenes Investigadores del I3A, Zaragoza, España, 2022.

Enlaces | BibTeX

Celotto, C; Sánchez, C; Abdollahpur, M; Sandberg, F; Rodriguez-Matas, J F; Laguna, P; Pueyo, E

Effects of Acetylcholine Release Spatial Distribution on the Frequency of Atrial Reentrant Circuits: a Computational Study Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Bukhari, H A; Sánchez, C; Laguna, P; Potse, M; Pueyo, E

Inter-individual differences in cell composition across the ventricular wall may explain variability in ECG response to serum potassium and calcium variations Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Gómez, M; Carro, J; Pueyo, E; Monasterio, V

An in Silico Investigation into the Role of SK Channels in Failing Ventricular Myocytes Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Rosales, R M; Mountris, K; Doblaré, M; Mazo, M; Pueyo, E

Ventricular Conduction System Modeling for Electrophysiological Simulation of the Porcine Heart Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Bukhari, H A; Sánchez, C; Pueyo, E; Potse, M

Accelerating stabilization of whole-heart models after changes in cycle length Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Sales, C; Palacios, S; Melero, J; Julián, I; Ramos, J; Martínez, J P; Mincholé, A; Pueyo, E

Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization Conferencia

Proceedings of the XLVIII International Conference on Computing in Cardiology, Tampere, Finland, 2022.

BibTeX

Pérez-Martínez, A; Oliván-Viguera, A; Pueyo, E

La endotelina-1 aumenta la heterogeneidad de la repolarización ventricular en cerdos con infarto crónico de miocardio Conferencia

XI Jornada de Jóvenes Investigadores e Investigadoras del I3A, Zaragoza, España, 2022.

Enlaces | BibTeX

Pérez-Martínez, A; Pueyo, E; Oliván-Viguera, A

Endothelin-1 enhances transmural heterogeneities in healthy porcine ventricular myocardium Conferencia

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

Enlaces | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Bellido-Morales, A; Sorribas-Berjón, J F; Matamala-Adell, M; Vázquez-Sancho, M; Fañanás-Mastral, J; Vallejo-Gil, J M; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Arbonés-Mainar, J M; Pueyo, E

SK channels characterization in the human ventricle: differences in expression levels and electrophysiological role in non-diseased and heart failure ventricles Conferencia

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

BibTeX

Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Pueyo, E; Oliván-Viguera, A

SK channels contribution to ventricular electrophysiology in heart failure patients Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

Enlaces | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; Pueyo, E

Endothelin-1 amplifies ventricular repolarization heterogeneities in chronic myocardial infarction pigs Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

Enlaces | BibTeX

Pérez-Martínez, A; Bellido-Morales, A; Fañanás-Mastral, J; Matamala-Adell, M; Sorribas-Berjón, J F; Vallejo-Gil, J M; Vázquez-Sancho, M; Ballester-Cuenca, C; Oliván-Viguera, A; Pueyo, E

Caracterización del papel de los canales SK en el remodelado ventricular producido por insuficiencia cardíaca Conferencia

II Congreso Anual Internacional de Estudiantes de Doctorado (CAED), Elche, España, 2022.

BibTeX

Oliván-Viguera, A; García-Otín, A L; Lozano-Gerona, J; Abarca-Lachen, E; García-Malinis, A J; Hamilton, K L; Gilaberte, Y; Pueyo, E; Köhler, R

Cell damage and apoptosis induced by TRPV4 activation in human melanoma cells and Hacat keratinocytes Conferencia

Reunión Anual de Sociedades de Biociencias 2022, Reunión conjunta SAIC SAI & FAIC SAFIS 2022, Medicina. Buenos Aires, Vol. 82 Supl. V - 2022 Buenos Aires, Argentina, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; García-Mendivil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age related cardiotoxicity of drugs Conferencia

Stem cells and stem cell models in disease & health (SCMiDH), Hasselt, Belgium, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new computational models to evaluate age-related drugs cardiotoxicity Conferencia

XI Jornada de Jóvenes Investigadores del Instituto de Investigación en Ingeniería de Aragón (I3A), Zaragoza, Spain, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new human models to determine age-related cardiotoxicity of drugs Conferencia

I ipIBA Day, Zaragoza, Spain, 2022.

BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Development of new human models to determine age-related cardiotoxicity of drugs Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Budapest, Hungría, 2022.

BibTeX

Garrido-Huéscar, E; Ordovás, L; Pueyo, E

Human cardiac models for investigation of age-related cardiotoxic effects of drug compounds Conferencia

XV CIBER-BBN Annual Conference, Valencia, Spain, 2022.

BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA Conferencia

XI Jornada de Jóvenes Investigadores, Zaragoza, Spain, 2022.

Enlaces | BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Towards advanced cardiac miRNA therapies through DNA-based nanostructures Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Budapest, Hungría, 2022.

Enlaces | BibTeX

Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L

Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA Conferencia

I iPIBA Day, Zaragoza, Spain, 2022.

BibTeX

Velarte, A; Otín, A; Guimera, A; Pueyo, E; Villa, R

Improving Signal Stability in a Multi-Electrode Array (MEA) System for Cardiac Biopsies Conferencia

Proceedings of the 37th Conference on Design of Circuits and Integrated Systems, Pamplona, Spain, 2022.

Enlaces | BibTeX

Velarte, A; Otín, A; Pueyo, E

Análisis y modelado de la impedancia de una matriz de microelectrodos (MEA) fabricados en oro mediante platino negro Conferencia

XI Jornada de Jóvenes Investigadores e Investigadoras del I3A, 2022.

Enlaces | BibTeX

2021

Artículos de revista

Hernández-Vicente, A; Hernando, D; Marín-Puyalto, J; Vicente-Rodríguez, G; Garatachea, N; Pueyo, E; Bailón, R

Validity of the Polar H7 Heart Rate Sensor for Heart Rate Variability Analysis during Exercise in Different Age, Body Composition and Fitness Level Groups Artículo de revista

En: Sensors, vol. 21, no. 902, 2021.

Enlaces | BibTeX

del Castillo, M González; Hernando, D; Orini, M; Laguna, P; Viik, J; Bailón, R; Pueyo, E

QT variability unrelated to RR variability during stress testing for identification of coronary artery disease Artículo de revista

En: Phil. Trans. R. Soc. A., vol. 379: 20200261, 2021.

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Palacios, S; Cygankiewicz, I; de Luna, A Bayés; Pueyo, E; Martínez, J P

Periodic Repolarization Dynamics as Predictor of Risk for Sudden Cardiac Death in Chronic Heart Failure Patients Artículo de revista

En: Scientific Reports, vol. 11:20546, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ferreira, D; Ruiz, J E; Bergasa, B; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Monitoring Blood Potassium Concentration in Hemodialysis Patients by Quantifying T-wave Morphology Dynamics Artículo de revista

En: Scientific reports, vol. 11, no. 3883, 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Nonlinear T-wave Time Warping-based Sensing Model for Non-invasive Personalized Blood Potassium Monitoring in Hemodialysis Patients Artículo de revista

En: Sensors, vol. 21, no. 2710, 2021.

Enlaces | BibTeX

Celotto, C; Sanchez, C; Mountris, K A; Laguna, P; Pueyo, E

Location of Parasympathetic Innervation Regions from Electrograms to Guide Atrial Fibrillation Ablation Therapy: An In Silico Modeling Study Artículo de revista

En: Frontiers in Physiology, vol. 12, no. 674197, 2021.

Enlaces | BibTeX

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