Address

Mariano Esquillor s/n, 50018, Zaragoza (Spain)

Contact Information

Call: +34 976 76 2963

Email: epueyo@unizar.es

Esther Pueyo Paules

Faculty Member

Website

http://www.estherpueyo.com

Biography

Esther Pueyo received the M.S. degree in Mathematics from the University of Zaragoza, Spain, in 1999. During 2000, she was a research student at the Department of Mathematics, University of Zaragoza, where she developed a minor thesis in the field of Calculus, supervised by Prof. José Garay. In 2001 she started her Ph.D. studies in Biomedical Engineering at the University of Zaragoza under the supervision of Prof. Pablo Laguna, with a grant supported by the Spanish government. Her Ph.D. studies aimed at developing signal processing techniques applied to the electrocardiogram with the purpose of investigating conditions predisposing to suffer cardiac arrhythmias. During that time, she also worked as an Assistant Professor of Signal Processing at the Department of Electronic Engineering and Communications and she was a visiting scholar at research centers in Portugal, Argentina and UK, with long research visits at St. George’s Hospital Medical School, London, UK, where she worked under the supervision of Prof. Marek Malik.

After finishing her PhD in December 2006, she moved to the University of Oxford, UK (2007-2009) to get postdoctoral training in computational modeling and simulation of cardiac electrophysiology. She worked with Dr. Blanca Rodríguez and Prof. Kevin Burrage in the construction of cell and tissue models to investigate cardiac pathologies and drug-induced effects associated with increased arrhythmic risk. Most of the studies conducted during her postdoctoral period involved collaborations with experts in cardiology and experimental physiology, mainly from Hungary, UK and Sweden.

In January 2011 she was appointed Associate Professor at the University of Zaragoza, Spain. During 2012-2015 she worked as Senior Researcher at the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) after having been awarded with a ‘Ramón y Cajal’ Senior Research fellowship by the Spanish government. At the University of Zaragoza and CIBER-BBN, she works with a group of postdoctoral researchers and PhD, MSc and undergraduate students in the development of methodologies for the analysis of simulated, experimental and clinical data. By combining ECG signal processing and electrophysiological modeling and simulation tools, her current research aims at shedding light on the mechanisms and manifestations of cardiac arrhythmias at scales ranging from cellular ion channels to the electrocardiogram and on the role of important modulators such as the Autonomic Nervous System.

Since October 2015 she is back to her Associate Professor position at the University of Zaragoza. She has participated as Principal Investigator and as Collaborator in different international, European, national and regional research projects. She is currently PI of the ERC Starting Grant project MODELAGE, funded with 1.5 M€, in which a systems biology approach is used to investigate the aging of the human heart.

Publications

162 registros « 1 de 4 »

2021

Artículos de revista

Bukhari, H A; Palmieri, F; Ramirez, J; Laguna, P; Ruiz, J E; Ferreira, D; Potse, M; Sánchez, C; Pueyo, E

Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate Artículo de revista

IEEE Trans Biomed Eng, 2021.

Enlaces | BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

Characterization of Spatio-Temporal Cardiac Action Potential Variability at Baseline and under Beta-Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction Artículo de revista

IEEE Journal of Biomedical and Health Informatics, 2021.

Enlaces | BibTeX

Hernández-Vicente, A; Hernando, D; Marín-Puyalto, J; Vicente-Rodríguez, G; Garatachea, N; Pueyo, E; Bailón, R

Validity of the Polar H7 Heart Rate Sensor for Heart Rate Variability Analysis during Exercise in Different Age, Body Composition and Fitness Level Groups Artículo de revista

Sensors, 21 (902), 2021.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ferreira, D; Ruiz, J E; Bergasa, B; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

Monitoring Blood Potassium Concentration in Hemodialysis Patients by Quantifying T-wave Morphology Dynamics Artículo de revista

Scientific reports, 11 (3883), 2021.

Enlaces | BibTeX

2020

Artículos de revista

Sampedro-Puente, D A; Fernandez-Bes, J; Virág, L; Varró, A; Pueyo, E

Data-driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-beat Variability Artículo de revista

IEEE Journal of Biomedical and Health Informatics, 2020.

Enlaces | BibTeX

Mountris, K A; Bourantas, G C; Millán, D; Joldes, G R; Miller, K; Pueyo, E; Wittek, A

Cell‐based maximum entropy approximants for three‐dimensional domains: Application in large strain elastodynamics using the meshless total Lagrangian explicit dynamics method Artículo de revista

Int J Numer Methods Eng, pp. 1-15, 2020.

Enlaces | BibTeX

van Duijvenboden, S; Porter, B; Pueyo, E; Sampedro-Puente, D A; Fernandez-Bes, J; Sidhu, B; Gould, J; Orini, M; Bishop, M; Hanson, B; Lambiase, P; Razavi, R; Rinaldi, C A; Gill, J S; Taggart, P

Complex interaction between low-frequency APD oscillations and beat-to-beat APD variability in humans is governed by the sympathetic nervous system Artículo de revista

Front. Physiol., 2020.

Enlaces | BibTeX

Sampedro-Puente, D A; Fernandez-Bes, J; Szentandrássy, N; Nánási, P; Taggart, P; Pueyo, E

Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis Artículo de revista

Front. Physiol, 10 (1547), 2020.

Enlaces | BibTeX

Corral-Acero, J; Margara, F; Marciniak, M; Rodero, C; Loncaric, F; Feng, Y; Gilbert, A; Fernandes, J F; Bukhari, H A; Wajdan, A; Villegas-Martinez, M; Sousa-Santos, M; Shamohammdi, M; Luo, H; Westphal, P; Leeson, P; DiAchille, P; Gurev, V; Mayr, M; Geris, L; Pathmanathan, P; Morrison, T; Cornelussen, R; Prinzen, F; Delhaas, T; Doltra, A; Sitges, M; Vigmond, E J; Zacur, E; Grau, V; Rodriguez, B; Remme, E W; Niederer, S; Mortier, P; McLeod, K; Potse, M; Pueyo, E; Bueno-Orovio, A; Lamata, P

The 'Digital Twin' to enable the vision of precision cardiology Artículo de revista

European Heart Journal, 2020.

Enlaces | BibTeX

Prado, N J; Muñoz, E M; Farias-Altamirano, L E; Aguiar, F; Ponce-Zumino, A Z; Sánchez, F J; Miatello, R M; Pueyo, E; Diez, E R

Reperfusion Arrhythmias Increase After Superior Cervical Ganglionectomy Due To Conduction Disorders And Changes In Repolarisation Artículo de revista

International Journal of Molecular Sciences, 21 (5), pp. 1804, 2020.

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Lozano-Gerona, J; Olivan-Viguera, A; Delgado-Wicke, P; Singh, V; Brown, B M; Tapia-Casellas, E; Pueyo, E; Valero, Sofía M; Garcia-Otín, A L; Giraldo, P; Abarca-Lachen, E; Surra, J C; Osada, J; Hamilton, K L; Raychaudhuri, S P; Marigil, M; Juarranz, A; Wulff, H; Miura, H; Gilaberte, Y; Köhler, R

Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis Artículo de revista

PlosOne, 15 (3), pp. e0222619, 2020.

Enlaces | BibTeX

Barrio, R; Coombes, S; Fenton, Desrochesand M F; Luther, S; Pueyo, E

Excitable Dynamics in Neural and Cardiac Systems Artículo de revista

Communications in Nonlinear Science and Numerical Simulation, 2020.

Enlaces | BibTeX

Barrio, R; Martínez, M A; Pérez, L; Pueyo, E

Bifurcations and slow-fast analysis in a cardiac cell model for investigation of early afterdepolarizations Artículo de revista

Mathematics, 8 (6), pp. 880, 2020.

Enlaces | BibTeX

Nanasi, P P; Pueyo, E; Virag, L

Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes Artículo de revista

Frontiers in Pharmacology, 2020.

Enlaces | BibTeX

Mountris, K A; Pueyo, E

The Radial Point Interpolation Mixed Collocation Method (RPIMC) for the solution of transient diffusion problems Artículo de revista

Eng Anal Bound Elem, 121 , pp. 207–216, 2020.

Enlaces | BibTeX

Oliván‑Viguera, A; Pérez‑Zabalza, M; García‑Mendívil, L; Mountris, K A; Orós‑Rodrigo, S; Ramos‑Marquès, E; Vallejo‑Gil, J M; Fresneda‑Roldán, P C; Fañanás‑Mastral, J; Vázquez‑Sancho, M; Matamala‑Adell, M; Sorribas‑Berjón, F; Bellido‑Morales, J A; Mancebón‑Sierra, F J; Vaca‑Núñez, A S; Ballester‑Cuenca, C; Marigil, M A; Pastor, C; Ordovás, L; Köhler, R; Diez, E; Pueyo, E

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors Artículo de revista

Sci Rep, 10 (19941), 2020.

Enlaces | BibTeX

Hernández-Vicente, A; Hernando, D; Santos-Lozano, A; Rodríguez-Romo, G; Vicente-Rodríguez, G; Pueyo, E; Bailón, R; Garatachea, N

Heart rate variability and exceptional longevity Artículo de revista

Frontiers in Physiology, 2020.

Enlaces | BibTeX

Milagro, J; Hernández-Vicente, A; Hernando, D; Casajús, J A; Garatachea, N; Bailón, R; Pueyo, E

Estimation of the second ventilatory threshold through ventricular repolarization profile analysis Artículo de revista

Scand J Med Sci Spo, 2020.

Enlaces | BibTeX

Bragard, J R; Camara, O; Echebarria, B; Giorda, Gerardo L; Pueyo, E; Saiz, J; Sebastián, R; Soudah, E; Vázquez, M

Cardiac Computational Modeling Artículo de revista

Rev Esp Cardiol, 2020.

Enlaces | BibTeX

Oliver-Gelabert, A; García-Mendívil, L; Vallejo-Gil, J M; Fresneda-Roldán, P C; Andelová, K; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, F; Ballester-Cuenca, C; Tribulova, N; Ordovás, L; Diez, E R; Pueyo, E

Automatic quantification of cardiomyocyte dimensions and connexin 43 lateralization in fluorescence images Artículo de revista

Biomolecules, 10 (9), pp. 1334, 2020.

Enlaces | BibTeX

Conferencias

Celotto, C; Sanchez, C; Mountris, K A; Laguna, P; Pueyo, E

SK Channel Block and Adrenergic Stimulation Counteract Acetylcholine-Induced Arrhythmogenic Effects in Human Atria Conferencia

42st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020.

Enlaces | BibTeX

Srinivasan, S; Bukhari, H A; Laguna, P; Sánchez, C; Pueyo, E

Analysis of T Wave Nonlinear Dynamics for Serum Potassium Monitoring in End-Stage Renal Disease Patients Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Celotto, C; Sánchez, C; Mountris, K A; Abdollahpur, M; Sandberg, F; Laguna, P; Pueyo, E

Oscillatory ACh Release Impact on f-Wave Frequency Modulation: an Experimentally-Based Computational Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Bueno-Palomeque, F L; Mountris, K A; Minchole, A; Ortigosa, N; Pueyo, E; Laguna, P

Changes in QRS and T-wave Loops Subsequent to an Increase in Left Ventricle Globularity as in Intrauterine Growth Restriction: a Simulation Study Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Laguna, P; Martínez, J P; Ramírez, J

Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Palacios, S; Martínez, J P; Pueyo, E

Sudden Cardiac Death Prediction in Chronic Heart Failure Patients by Periodic Repolarization Dynamics Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Pérez-Zabalza, M; Diez, E R; Rhyins, J; Mountris, K A; Segovia-Roldán, M; Oliván-Viguera, A; Pueyo, E

Improved methods for processing optical mapping signals from human left ventricular tissues at baseline and following adrenergic stimulation Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Mountris, K A; Pueyo, E

Next-generation in-silico Cardiac Electrophysiology through Immersed Grid Meshfree Modelling Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Palacios, S; Cygankiewicz, I; Bayés-de-Luna, A; Martínez, J P; Pueyo, E

Predicción de muerte súbita en pacientes con insuficiencia cardíaca crónica mediante el estudio de la dinámica periódica de la repolarización Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Ferreira, D; Martín-Yebra, A; Pueyo, E; Laguna, P; Martínez, J P; Ramírez, J

Monitorización en diálisis de la Concentración de Potasio en Sangre mediante los cambios en la morfología multi-lead de la onda T: Comparación Entre usar la transformación en Componentes Periódicas y Principales Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

Caracterización in silico de la duración de la repolarización y su variabilidad en el síndrome de QT Largo Tipo1 bajo estimulación β adrenérgica Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Viik, J; Laguna, P

Retardo entre QT y RR en registros de prueba de esfuerzo como indicador de la heterogeneidad de la repolarización ventricular Conferencia

XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB, Valladolid, España, 2020.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Laguna, P

Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings Conferencia

11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO), 2020.

Enlaces | BibTeX

Pérez-Martínez, C; Pueyo, E; Martínez, J P; Viik, J; Laguna, P

Characterization of Impaired Ventricular Repolarization by Quantification of QT Delayed Response to Heart Rate Changes in Stress Test Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Sampedro-Puente, D A; Raphel, F; Fernandez-Bes, J; Laguna, P; Lombardi, D; Pueyo, E

In Silico Characterization of Repolarization Duration and Variability in the Long QT1 Syndrome Under β-Adrenergic Stimulation Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

BibTeX

Capítulos de libros

Prado, N J; Segovia-Roldan, M; Diez, E R; Pueyo, E

Melatonin for a Healthy Heart Rhythm Capítulo de libro

IntechOpen, 2020.

Enlaces | BibTeX

2019

Artículos de revista

Ramírez, J; Duijvenboden, Van S; Aung, N; Laguna, P; Pueyo, E; Tinker, A; Lambiase, P; Orini, M; Munroe, P

Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics Artículo de revista

Circulation: Arrhythmia and Electrophysiology, 2019.

Enlaces | BibTeX

Sampedro-Puente, D A; Fernandez-Bes, J; Porter, B; Duijvenboden, S; Taggart, P; Pueyo, E

Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat variability of celullar ventricular repolarization in response to sympathetic stimulation: Implications for arrhythmogenesis Artículo de revista

Frontiers in Physiology, 10 (916), pp. 1-18, 2019.

Enlaces | BibTeX

Sampedro-Puente, D A; Fernández-Bes, J; Szentandrássy, N; Nánasi, P; Pueyo, E

Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis Artículo de revista

Front. Physiol., 2019.

Enlaces | BibTeX

Palacios, S; Caiani, E G; Landreani, F; Martínez, J P; Pueyo, E

Long-term microgravity exposure increases ECG repolarization instability manifested by low-frequency oscillations of T-wave vector Artículo de revista

Front. Physiol., 10 (1510), 2019.

Enlaces | BibTeX

Valero, M S; Ramón-Gimenez, M; Lozano-Gerona, J; Delgado-Wicke, P; Calmarza, P; Olivan-Viguera, A; López, V; Garcia-Otín, Á L; Valero, S; Pueyo, E; Hamilton, K L; Miura, H; Köhler, R

Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility Artículo de revista

International Journal of Molecular Sciences, 20 (1193), 2019.

Enlaces | BibTeX

Conferencias

Bukhari, H A; Palmieri, F; Ferreira, D; Potse, M; Ramírez, J; Laguna, P; Sánchez, C; Pueyo, E

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Serum Potassium Levels Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Celotto, C; Sánchez, C; Laguna, P; Pueyo, E

Calcium-Activated Potassium Channel Inhibition in Autonomically Stimulated Human Atrial Myocytes Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Palmieri, F; Gomis, P; Ruiz, J E; Bergasa, B; Ferreira, D; Martín-Yebra, A; Bukhari, H A; Pueyo, E; Martínez, J P; Ramírez, J; Laguna, P

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Monasterio, V; Pueyo, E; Rodríguez, J F; Carro, J

Influence of the Stimulation Current on the Differences between Cell and Tissue Electrophysiological Simulations Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Palacios, S; Caiani, E; Pueyo, E; Martínez, J P

Response of Ventricular Repolarization to Simulated Microgravity Measured by Periodic Repolarization Dynamics Using Phase-Rectified Signal Averaging Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Mountris, K A; Sánchez, C; Pueyo, E

A Novel Paradigm for in Silico Simulation of Cardiac Electrophysiology through the Mixed Collocation Meshless Petrov-Galerkin Method Conferencia

Proceedings of the XLVI International Conference on Computing in Cardiology, Singapore, 2019.

BibTeX

Pueyo, E

Combined Experimental and Computational Research into Cardiac-Neural Interactions and Arrhythmias. Invited talk Conferencia

41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Berlin, Germany, 2019.

BibTeX

Ramos, E; García, L; Oliveros, J C; Torres, R; López, A; Oliván, A; Vallejo, J M; Fresneda, P C; Fañanás, J; Matamala, M; Sorribas, F; Vázquez, M; Ballester, C; Ordovás, L; Pueyo, E

The role of microRNAs in age-related remodeling of the human left ventricle Conferencia

European Society of Cardiology (ESC), Poster , 2019.

BibTeX

García, L; Smisdom, N; Mountris, K A; Oliván, A; Vallejo, J M; Fresneda, P C; Fañanás, J; Matamala, M; Sorribas, F; Vázquez, M; Ballester, C; Wolfs, E; Driesen, R B; Ordovás, L; Pueyo, E

Histological characterization of age-related remodeling in human left ventricle by second harmonic generation and lipofuscin content Conferencia

European Society of Cardiology (ESC), Poster , 2019.

BibTeX

162 registros « 1 de 4 »
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