Faculty Member

Call: +34 876 555462

Email: mariapzabalza@unizar.es

Address: Campus Río Ebro, Edificio I+D, Lab 5.1.01B, C/ Mariano Esquillor, s/n – 50018 Zaragoza (Spain)

ABOUT ME

María Pérez Zabalza received the MSc in Telecommunication Engineering from the Public University of Navarre (UPNA), Spain, in 1999. After working for 6 years as software engineer in different private companies in Navarre, Madrid and Barcelona, she studied the Master Degree in Biomedical Engineering from the Polytechnic University of Catalonia (UPC), Barcelona. As a result of this, in 2005, she started her career as a researcher in the Institute Guttmann – Neurorehabilitation Hospital, Barcelona, performing, analysing and studying multichannel surface electromyography (sEMG) of patients with incomplete spinal cord injury. In 2008 she started her PhD studies in Neuroscience at the University of Barcelona under the supervision of Dr. Maria Victoria Sanchez (Idibaps, Barcelona) and Dr. Maurizio Mattia (Istituto Superiore di Sanita, Rome), finishing in 2013. Her thesis work focused on the study and mathematical analysis of brain signals to understand the mechanisms that modulate a specific brain rhythm, and their possible alterations triggered by different types of pathologies. In September of 2016, she got a postdoc position at the Engineering Fluid Dynamics department at the University of Twente (Netherlands). For two years she studied different biomedical signals to investigate mechanisms of action of High Flow Therapy and the physiological impact on respiratory mechanics, to find possible Biomarkers which help clinicians deliver this technique in a more optimal and efficient way.

PUBLICATIONS

2024

Journal Articles

Rosales, R M; Mountris, K A; Oliván-Viguera, A; Pérez-Zabalza, M; Cedillo-Servin, G; Iglesias-García, O; Hrynevich, A; Castilho, M; Malda, J; Prósper, F; Doblaré, M; Mazo, M M; Pueyo, E

Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction Journal Article

In: Computers in Biology and Medicine, vol. 171, no. 108044, 2024.

Links | BibTeX

Conferences

Pérez-Zabalza, M; Peláez-Coca, M D; Lozano, M T; Bolea, J

Exploring Nonlinear Heart Rate Variability for Assessing the Autonomic Nervous System in Hyperbaric Environments Conference

13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO), 2024.

Links | BibTeX

2023

Journal Articles

García-Mendívil, L; Pérez-Zabalza, M; Oliver-Gelabert, A; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; André-Bellido, J A; Vaca-Núñez, A S; Ballester-Cuenca, C; Diez, E R; Ordovás, L; Pueyo, E

Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk Journal Article

In: Research, vol. 6, iss. 0254, 2023.

Links | BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Duwé, S; Ordovás, L; Pueyo, E

Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy Journal Article

In: Star Protocols, vol. 4, no. 102730, 2023.

Links | BibTeX

Conferences

Bueno, J M; Martínez-Ojeda, R M; Asensio, M C; García-Mendívil, L; Pérez-Zabalza, M; Ordovás, L; Pueyo, E

Age-related Changes in Tissue Structure of the Heart Left Ventricle Assessed with Multiphoton Microscopy Conference

Optica Biophotonics Congress: Optics in the Life Sciences, Vancouver (Canada), 2023.

BibTeX

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Vallejo-Gil, J M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Verfaillie, C M; Pueyo, E; Ordovás, L

Progerin is an unlikely contributor to natural cardiac aging, but promotes age-related phenotypes in vitro Conference

Cellular Biology of the Heart & Myocardial Function (CBFH) Biennial meeting 2023, Naples (Italy), 2023.

BibTeX

García-Mendívil, L; Pérez, M; Rosales, R; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Ordovás, L; Pueyo, E

Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia Conference

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

Links | BibTeX

2022

Journal Articles

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K; Duwé, S; Smisdom, N; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Oliván-Viguera, A; Diez, E; Ordovás, L; Pueyo, E

Analysis of age-related left ventricular collagen remodeling in living donors: implications in arrhythmogenesis Journal Article

In: iScience, 2022.

Links | BibTeX

Conferences

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres-Pérez, R; Ramos-Marqués, E; Pueyo, E; Ordovás, L

Envejecimiento cardíaco humano: transcriptómica y desarrollo de modelos celulares Conference

II Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernández, Elche, 2022.

BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Duwé, S; Ordovás, L; Pueyo, E

Caracterización del remodelado del colágeno asociado a la edad en el ventrículo izquierdo humano de donantes vivos y sus implicaciones en la generación de arritmias Conference

XI Jornada de Jóvenes Investigadores del I3A, 2022.

Links | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Bellido-Morales, A; Sorribas-Berjón, J F; Matamala-Adell, M; Vázquez-Sancho, M; Fañanás-Mastral, J; Vallejo-Gil, J M; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Arbonés-Mainar, J M; Pueyo, E

SK channels characterization in the human ventricle: differences in expression levels and electrophysiological role in non-diseased and heart failure ventricles Conference

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

BibTeX

Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Pueyo, E; Oliván-Viguera, A

SK channels contribution to ventricular electrophysiology in heart failure patients Conference

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

Links | BibTeX

Garrido-Huéscar, E; García-Mendivil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age related cardiotoxicity of drugs Conference

Stem cells and stem cell models in disease & health (SCMiDH), Hasselt, Belgium, 2022.

Links | BibTeX

Garrido-Huéscar, E; García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age-related cardiotoxicity of drugs Conference

Stem Cells and Stem Cell Models in Disease and Health (SCMIDH), Hasselt, Belgium, 2022.

BibTeX

2021

Journal Articles

Ramos-Marquès, E; García-Mendívil, L; Pérez-Zabalza, M; Santander-Badules, H; Srinivasan, S; Oliveros, J C; Torres-Pérez, R; Cebollada, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Jiménez-Navarro, M; Villaescusa, J M; Garrido-Huéscar, E; Segovia-Roldán, M; Oliván-Viguera, A; Gómez-González, C; Muñiz, G; Diez, E; Ordovás, L; Pueyo, E

Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution Journal Article

In: Aging Cell, vol. 00:e13383, pp. 1-16, 2021.

Links | BibTeX

Conferences

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

Envejecimiento cardiaco humano: transcriptómica y desarrollo de modelos celulares de envejecimiento Conference

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Links | BibTeX

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

In vivo and in vitro cardiac aging: developing of cellular aging models Conference

XIX Congreso de la Sociedad Española de Biología Celular. Póster, 2021.

BibTeX

Pérez, M; García-Mendívil, L; Mountris, K; Smisdom, N; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Matamala-Adell, M; Vázquez-Sancho, M; Mancebón-Sierra, F Javier; Vaca-Núñez, A Sebastián; Ballester-Cuenca, C; Olivan-Viguera, A; Ordovás, L; Pueyo, E

Age-associated changes in fibrosis amount and spatial organization and its effects on human ventricular electrophysiology Conference

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Links | BibTeX

García-Mendívil, L; Smisdom, N; Duwe, S; Mountris, K; Srinivasan, S; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Olivan-Viguera, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, F; Ballester-Cuenca, C; Diez, E; Ordovás, L; Pueyo, E

Caracterización del remodelado cardiaco asociado a la edad en el ventrículo izquierdo humano Conference

Primer congreso anual de estudiantes de doctorado de la Universidad Miguel Hernández. Comunicación oral, 2021.

BibTeX

2020

Journal Articles

Sanchez-Vives, M V; Barbero-Castillo, A; Perez-Zabalza, M; Reig, R

GABAB receptor-modulation of thalamocortical dynamics and synaptic plasticity Journal Article

In: Neuroscience, vol. 456, pp. 131-142, 2020.

Links | BibTeX

Oliván‑Viguera, A; Pérez‑Zabalza, M; García‑Mendívil, L; Mountris, K A; Orós‑Rodrigo, S; Ramos‑Marquès, E; Vallejo‑Gil, J M; Fresneda‑Roldán, P C; Fañanás‑Mastral, J; Vázquez‑Sancho, M; Matamala‑Adell, M; Sorribas‑Berjón, F; Bellido‑Morales, J A; Mancebón‑Sierra, F J; Vaca‑Núñez, A S; Ballester‑Cuenca, C; Marigil, M A; Pastor, C; Ordovás, L; Köhler, R; Diez, E; Pueyo, E

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors Journal Article

In: Sci Rep, vol. 10, no. 19941, 2020.

Links | BibTeX

Conferences

Pérez-Zabalza, M; Diez, E R; Rhyins, J; Mountris, K A; Segovia-Roldán, M; Oliván-Viguera, A; Pueyo, E

Improved methods for processing optical mapping signals from human left ventricular tissues at baseline and following adrenergic stimulation Conference

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Links | BibTeX