Faculty Member

Call: +34 876 555462

Email: mariapzabalza@unizar.es

Address: Campus Río Ebro, Edificio I+D, Lab 5.1.01B, C/ Mariano Esquillor, s/n – 50018 Zaragoza (Spain)

ABOUT ME

María Pérez Zabalza received the MSc in Telecommunication Engineering from the Public University of Navarre (UPNA), Spain, in 1999. After working for 6 years as software engineer in different private companies in Navarre, Madrid and Barcelona, she studied the Master Degree in Biomedical Engineering from the Polytechnic University of Catalonia (UPC), Barcelona. As a result of this, in 2005, she started her career as a researcher in the Institute Guttmann – Neurorehabilitation Hospital, Barcelona, performing, analysing and studying multichannel surface electromyography (sEMG) of patients with incomplete spinal cord injury. In 2008 she started her PhD studies in Neuroscience at the University of Barcelona under the supervision of Dr. Maria Victoria Sanchez (Idibaps, Barcelona) and Dr. Maurizio Mattia (Istituto Superiore di Sanita, Rome), finishing in 2013. Her thesis work focused on the study and mathematical analysis of brain signals to understand the mechanisms that modulate a specific brain rhythm, and their possible alterations triggered by different types of pathologies. In September of 2016, she got a postdoc position at the Engineering Fluid Dynamics department at the University of Twente (Netherlands). For two years she studied different biomedical signals to investigate mechanisms of action of High Flow Therapy and the physiological impact on respiratory mechanics, to find possible Biomarkers which help clinicians deliver this technique in a more optimal and efficient way.

PUBLICATIONS

2024

Artículos de revista

Rosales, R M; Mountris, K A; Oliván-Viguera, A; Pérez-Zabalza, M; Cedillo-Servin, G; Iglesias-García, O; Hrynevich, A; Castilho, M; Malda, J; Prósper, F; Doblaré, M; Mazo, M M; Pueyo, E

Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction Artículo de revista

En: Computers in Biology and Medicine, vol. 171, no 108044, 2024.

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2023

Artículos de revista

García-Mendívil, L; Pérez-Zabalza, M; Oliver-Gelabert, A; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; André-Bellido, J A; Vaca-Núñez, A S; Ballester-Cuenca, C; Diez, E R; Ordovás, L; Pueyo, E

Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk Artículo de revista

En: Research, vol. 6, iss. 0254, 2023.

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García-Mendívil, L; Pérez-Zabalza, M; Duwé, S; Ordovás, L; Pueyo, E

Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy Artículo de revista

En: Star Protocols, vol. 4, no 102730, 2023.

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Conferencias

Bueno, J M; Martínez-Ojeda, R M; Asensio, M C; García-Mendívil, L; Pérez-Zabalza, M; Ordovás, L; Pueyo, E

Age-related Changes in Tissue Structure of the Heart Left Ventricle Assessed with Multiphoton Microscopy Conferencia

Optica Biophotonics Congress: Optics in the Life Sciences, Vancouver (Canada), 2023.

BibTeX

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Vallejo-Gil, J M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Verfaillie, C M; Pueyo, E; Ordovás, L

Progerin is an unlikely contributor to natural cardiac aging, but promotes age-related phenotypes in vitro Conferencia

Cellular Biology of the Heart & Myocardial Function (CBFH) Biennial meeting 2023, Naples (Italy), 2023.

BibTeX

García-Mendívil, L; Pérez, M; Rosales, R; Vallejo-Gil, J M; Fañanás-Mastral, J; Vázquez-Sancho, M; Bellido‑Morales, J A; Vaca‑Núñez, A S; Ballester-Cuenca, C; Ordovás, L; Pueyo, E

Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia Conferencia

Proceedings of the XLIX International Conference on Computing in Cardiology, Atlanta, USA, 2023.

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2022

Artículos de revista

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K; Duwé, S; Smisdom, N; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Oliván-Viguera, A; Diez, E; Ordovás, L; Pueyo, E

Analysis of age-related left ventricular collagen remodeling in living donors: implications in arrhythmogenesis Artículo de revista

En: iScience, 2022.

Enlaces | BibTeX

Conferencias

García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres-Pérez, R; Ramos-Marqués, E; Pueyo, E; Ordovás, L

Envejecimiento cardíaco humano: transcriptómica y desarrollo de modelos celulares Conferencia

II Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernández, Elche, 2022.

BibTeX

García-Mendívil, L; Pérez-Zabalza, M; Mountris, K M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Duwé, S; Ordovás, L; Pueyo, E

Caracterización del remodelado del colágeno asociado a la edad en el ventrículo izquierdo humano de donantes vivos y sus implicaciones en la generación de arritmias Conferencia

XI Jornada de Jóvenes Investigadores del I3A, 2022.

Enlaces | BibTeX

Oliván-Viguera, A; Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Bellido-Morales, A; Sorribas-Berjón, J F; Matamala-Adell, M; Vázquez-Sancho, M; Fañanás-Mastral, J; Vallejo-Gil, J M; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Arbonés-Mainar, J M; Pueyo, E

SK channels characterization in the human ventricle: differences in expression levels and electrophysiological role in non-diseased and heart failure ventricles Conferencia

46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE), Toledo, España, 2022.

BibTeX

Pérez-Martínez, A; García-Mendívil, L; López-Yus, M; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Pérez-Zabalza, M; Köehler, R; Pueyo, E; Oliván-Viguera, A

SK channels contribution to ventricular electrophysiology in heart failure patients Conferencia

Frontiers in CardioVascular Biomedicine (FCVB), Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022 Budapest, Hungría, 2022.

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Garrido-Huéscar, E; García-Mendivil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age related cardiotoxicity of drugs Conferencia

Stem cells and stem cell models in disease & health (SCMiDH), Hasselt, Belgium, 2022.

Enlaces | BibTeX

Garrido-Huéscar, E; García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez-Zabalza, M; Pueyo, E; Ordovás, L

Development of new human models to determine age-related cardiotoxicity of drugs Conferencia

Stem Cells and Stem Cell Models in Disease and Health (SCMIDH), Hasselt, Belgium, 2022.

BibTeX

2021

Artículos de revista

Ramos-Marquès, E; García-Mendívil, L; Pérez-Zabalza, M; Santander-Badules, H; Srinivasan, S; Oliveros, J C; Torres-Pérez, R; Cebollada, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, J F; Bellido-Morales, J A; Mancebón-Sierra, F J; Vaca-Núñez, A S; Ballester-Cuenca, C; Jiménez-Navarro, M; Villaescusa, J M; Garrido-Huéscar, E; Segovia-Roldán, M; Oliván-Viguera, A; Gómez-González, C; Muñiz, G; Diez, E; Ordovás, L; Pueyo, E

Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution Artículo de revista

En: Aging Cell, vol. 00:e13383, pp. 1-16, 2021.

Enlaces | BibTeX

Conferencias

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

Envejecimiento cardiaco humano: transcriptómica y desarrollo de modelos celulares de envejecimiento Conferencia

X Jornada de Jóvenes Investigadores I3A. Comunicación oral, 2021.

Enlaces | BibTeX

García-Mendívil, L; Hernández, N; Sánchez, M; Pérez-Zabalza, M; Garrido-Huéscar, E; Oliveros, J C; Torres, R; Ramos, E; Pueyo, E; Ordovás, L

In vivo and in vitro cardiac aging: developing of cellular aging models Conferencia

XIX Congreso de la Sociedad Española de Biología Celular. Póster, 2021.

BibTeX

Pérez, M; García-Mendívil, L; Mountris, K; Smisdom, N; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Matamala-Adell, M; Vázquez-Sancho, M; Mancebón-Sierra, F Javier; Vaca-Núñez, A Sebastián; Ballester-Cuenca, C; Olivan-Viguera, A; Ordovás, L; Pueyo, E

Age-associated changes in fibrosis amount and spatial organization and its effects on human ventricular electrophysiology Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Brno, Czech Republic, 2021.

Enlaces | BibTeX

García-Mendívil, L; Smisdom, N; Duwe, S; Mountris, K; Srinivasan, S; Pérez, M; Luján, L; Wolfs, E; Driesen, R B; Olivan-Viguera, A; Vallejo-Gil, J M; Fresneda-Roldán, P C; Fañanás-Mastral, J; Vázquez-Sancho, M; Matamala-Adell, M; Sorribas-Berjón, F; Ballester-Cuenca, C; Diez, E; Ordovás, L; Pueyo, E

Caracterización del remodelado cardiaco asociado a la edad en el ventrículo izquierdo humano Conferencia

Primer congreso anual de estudiantes de doctorado de la Universidad Miguel Hernández. Comunicación oral, 2021.

BibTeX

2020

Artículos de revista

Sanchez-Vives, M V; Barbero-Castillo, A; Perez-Zabalza, M; Reig, R

GABAB receptor-modulation of thalamocortical dynamics and synaptic plasticity Artículo de revista

En: Neuroscience, vol. 456, pp. 131-142, 2020.

Enlaces | BibTeX

Oliván‑Viguera, A; Pérez‑Zabalza, M; García‑Mendívil, L; Mountris, K A; Orós‑Rodrigo, S; Ramos‑Marquès, E; Vallejo‑Gil, J M; Fresneda‑Roldán, P C; Fañanás‑Mastral, J; Vázquez‑Sancho, M; Matamala‑Adell, M; Sorribas‑Berjón, F; Bellido‑Morales, J A; Mancebón‑Sierra, F J; Vaca‑Núñez, A S; Ballester‑Cuenca, C; Marigil, M A; Pastor, C; Ordovás, L; Köhler, R; Diez, E; Pueyo, E

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors Artículo de revista

En: Sci Rep, vol. 10, no 19941, 2020.

Enlaces | BibTeX

Conferencias

Pérez-Zabalza, M; Diez, E R; Rhyins, J; Mountris, K A; Segovia-Roldán, M; Oliván-Viguera, A; Pueyo, E

Improved methods for processing optical mapping signals from human left ventricular tissues at baseline and following adrenergic stimulation Conferencia

Proceedings of the XLVII International Conference on Computing in Cardiology, Rimini, Italy, 2020.

Enlaces | BibTeX