Faculty Member
Call: +34 876 555478
Email: minchole@unizar.es
Address: Campus Río Ebro, Edificio I+D, Lab 6.1.08, C/ Mariano Esquillor, s/n – 50018 Zaragoza (Spain)
ABOUT ME
Ana Mincholé graduated in Physics from the University of Zaragoza, Spain in 2002. She also obtained an MSc with distinction at Chalmers University of Technology, Gothenburg, Sweden, in the MSc program “Nanoscale Physics and Engineering”. She then started a PhD in Biomedical Engineering at the Communication Technology Group at the University of Zaragoza, Spain supervised by Prof. Pablo Laguna. Her PhD focused on the analysis of the electrocardiographic signal and the development of novel ECG biomarkers for the stratification of arrhythmic risk. During her PhD, she conducted research visits to the Laboratory for Biomedical Computer Systems and Imaging at the University of Ljubljana, Slovenia, with Prof. Franc Jager, and to the Argentinian Institute of Mathematics, CONICET with Dr Pedro Arini and Dr Marcelo Risk. After her PhD and a short postdoc experience in the European preDiCt project at the University of Oxford, she was awarded a Marie Curie Intra-European Fellowship for Career Development and joined Prof. Blanca Rodriguez’ group at the Department of Computer Science at the University of Oxford, UK. After the fellowship, she continued working at the University of Oxford holding the position of Senior Research Associate until 2019. Then, she moved to the University of Zaragoza to join the Multiscale in Mechanical and Biological Engineering group within the European PRIMAGE project where she applied her expertise in multiscale modelling and simulation and high-performance computing to model tumour growth. In 2020, she was awarded a Ramón y Cajal Senior Research Fellowship from the Spanish Ministry of Science and Innovation and joined the Biomedical Signal Interpretation and Computational Simulation (BSICoS) group at the University of Zaragoza in 2021.
Her research interests include the development and evaluation of synergistic data-driven approaches where modelling and simulation are used to integrate biomedical data at different scales in the investigation of cardiac pathological conditions. This is in line with her expertise in the combination of computational modelling and simulation of physiological processes, biomedical signal analysis and machine learning techniques to stratify risk either drug-induced or due to pathological conditions.
PUBLICATIONS
2012
Conferencias
Ramírez, J; Mincholé, A; Laguna, P; Pueyo, E
Characterization of Cardiac Repolarization Response to Heart Rate Changes Provoked by a Tilt Test Conferencia
XXXIX International Conference on Computing in Cardiology, Kracow, Poland, 2012.
@conference{Ramirez_conf2012c,
title = {Characterization of Cardiac Repolarization Response to Heart Rate Changes Provoked by a Tilt Test},
author = {J Ramírez and A Mincholé and P Laguna and E Pueyo},
url = {https://drive.google.com/file/d/1v9OAJsY7ecizCnCadRMBSpN_QP3Oa-Xh/view},
year = {2012},
date = {2012-01-01},
booktitle = {XXXIX International Conference on Computing in Cardiology},
pages = {673-676},
address = {Kracow, Poland},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Ramírez, J; Mincholé, A; Laguna, P; Pueyo, E
Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB), 2012, ISBN: 10:84-616-2147-6; 13:978-84-616-2147-7.
@conference{Ramirez_conf2012b,
title = {Caracterización de la Respuesta de la Repolarización a Cambios en el Ritmo Cardiaco Provocados por una Prueba de “Tilt”},
author = {J Ramírez and A Mincholé and P Laguna and E Pueyo},
url = {https://drive.google.com/file/d/18jUXG81Gksv39Kn65rSzh1bR1yTb3Iui/view},
isbn = {10:84-616-2147-6; 13:978-84-616-2147-7},
year = {2012},
date = {2012-01-01},
booktitle = {Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB)},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2011
Artículos de revista
Mincholé, A; Pueyo, E; Rodríguez, J F; Zacur, E; Doblaré, M; Laguna, P
Quantification of Restitution Dispersion from the Dynamic Changes of the T wave peak to end, measured at the Surface ECG Artículo de revista
En: IEEE Transactions Biomedical Engineering, vol. 58, no 5, pp. 1172-1182, 2011.
@article{Minchole2011,
title = {Quantification of Restitution Dispersion from the Dynamic Changes of the T wave peak to end, measured at the Surface ECG},
author = {A Mincholé and E Pueyo and J F Rodríguez and E Zacur and M Doblaré and P Laguna},
url = {https://drive.google.com/file/d/1oW1QEWniJ5LPrnDTIL8jL0M2mek2wrDq/view},
doi = {10.1109/TBME.2010.2097597},
year = {2011},
date = {2011-01-01},
journal = {IEEE Transactions Biomedical Engineering},
volume = {58},
number = {5},
pages = {1172-1182},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Conferencias
Mincholé, A; Sörnmo, L; Laguna, P
ECG-based detection of body position changes using a Laplacian noise model Conferencia
33nd Annual International Conference of the IEEE EMBS, Boston, USA, 2011.
@conference{Minchole_conf2011,
title = {ECG-based detection of body position changes using a Laplacian noise model},
author = {A Mincholé and L Sörnmo and P Laguna},
url = {https://drive.google.com/file/d/1v4lcq8Vth0lwxnmEAkR9iULTjPBcCHcM/view},
year = {2011},
date = {2011-01-01},
booktitle = {33nd Annual International Conference of the IEEE EMBS},
pages = {6931-6934},
address = {Boston, USA},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Tesis doctorales
Mincholé, A
Automatic detection of ischemia in Holter recordings and search for new risk markes from the electrocardiographic signal Tesis doctoral
Zaragoza University, 2011.
@phdthesis{Minchole_Thesis,
title = {Automatic detection of ischemia in Holter recordings and search for new risk markes from the electrocardiographic signal},
author = {A Mincholé},
url = {https://drive.google.com/file/d/1RMkia7Ek5vXiEZEcPzcmDtAPiBkWhYje/view},
year = {2011},
date = {2011-01-01},
urldate = {2011-01-01},
school = {Zaragoza University},
keywords = {},
pubstate = {published},
tppubtype = {phdthesis}
}
2010
Artículos de revista
Mincholé, A; Jager, F; Laguna, P
Discrimination Between Ischemic and Artifactual ST Segment Events in Holter Recordings Artículo de revista
En: Biomedical signal processing and control, vol. 5, pp. 21-31, 2010.
@article{Minchole2010,
title = {Discrimination Between Ischemic and Artifactual ST Segment Events in Holter Recordings},
author = {A Mincholé and F Jager and P Laguna},
url = {https://drive.google.com/file/d/11GcDKpPNwu13Yr5sJVjDzRD3O_X7wr4N/view},
doi = {10.1016/j.bspc.2009.09.001},
year = {2010},
date = {2010-01-01},
journal = {Biomedical signal processing and control},
volume = {5},
pages = {21-31},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Conferencias
Mincholé, A; Pueyo, E; Rodriguez, J F; Zacur, E; Doblaré, M; Laguna, P
Evaluation of a Method for Quantification of Restitution Dispersion from the surface ECG Conferencia
XXXVII International Conference on Computers in Cardiology, Belfast, UK, 2010.
@conference{Minchole_conf2010c,
title = {Evaluation of a Method for Quantification of Restitution Dispersion from the surface ECG},
author = {A Mincholé and E Pueyo and J F Rodriguez and E Zacur and M Doblaré and P Laguna},
url = {https://drive.google.com/file/d/1T6AQAZsXX5-3guJ3X6K27_LWfb1At6J1/view},
year = {2010},
date = {2010-01-01},
booktitle = {XXXVII International Conference on Computers in Cardiology},
pages = {773-776},
address = {Belfast, UK},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Mincholé, A; Pueyo, E; Laguna, P
Dispersion of APD restitution quantified from the surface ECG Conferencia
35th Research and Technology transfer in computerized electrocardiology, 2010.
@conference{Minchole_conf2010b,
title = {Dispersion of APD restitution quantified from the surface ECG},
author = {A Mincholé and E Pueyo and P Laguna},
url = {https://drive.google.com/file/d/1s_qWuyRTmgW2ULYRNLis8LH_U-bYMx1a/view},
year = {2010},
date = {2010-01-01},
booktitle = {35th Research and Technology transfer in computerized electrocardiology},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2009
Conferencias
Mincholé, A; Pueyo, E; Laguna, P
Diferencias Transmurales en la adaptación a cambios del ritmo cardiaco medidas sobre el ECG Conferencia
XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, 2009.
@conference{Minchole_c209,
title = {Diferencias Transmurales en la adaptación a cambios del ritmo cardiaco medidas sobre el ECG},
author = {A Mincholé and E Pueyo and P Laguna},
url = {https://drive.google.com/file/d/1a2kI_akBaZah4zfNn475taOe47q2Itn3/view},
year = {2009},
date = {2009-01-01},
booktitle = {XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica},
pages = {597-600},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Orini, M; Bailón, R; Mincholé, A; Mainardi, L; Laguna, P
XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, 2009.
@conference{Orini_c209,
title = {Metodología para el seguimiento de las dinámicas cardiovasculares a través de la coherencia tiempo-frecuencia},
author = {M Orini and R Bailón and A Mincholé and L Mainardi and P Laguna},
url = {https://drive.google.com/file/d/1MosvrVl1e4EBubFt67BjEa4ca4uMtZ5l/view},
year = {2009},
date = {2009-01-01},
booktitle = {XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica},
pages = {629-632},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Mincholé, A; Pueyo, E; Laguna, P
XXXVI Ann. Conf. Computers in Cardiology, Park City, 2009.
@conference{Minchole_c309,
title = {Transmural Differences in Rate Adaptation of Repolarization Duration Quantified from ECG Repolarization Interval Dynamics},
author = {A Mincholé and E Pueyo and P Laguna},
url = {https://drive.google.com/file/d/1Xh6sXFUfUm8bBiSyUwXm6tIvUCNxagV2/view},
year = {2009},
date = {2009-01-01},
booktitle = {XXXVI Ann. Conf. Computers in Cardiology},
pages = {597-600},
address = {Park City},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Orini, M; Bailón, R; Mainardi, L; Mincholé, A; Laguna, P
XXXVI Ann. Conf. Computers in Cardiology, Park City, 2009.
@conference{Orini_c309,
title = {Continuous Quantification of Spectral Coherence Using Quadratic Time-Frequency Distributions: Error Analysis and Application},
author = {M Orini and R Bailón and L Mainardi and A Mincholé and P Laguna},
url = {https://drive.google.com/file/d/1oOenbkZpwEXVyUOC7uAHjfpMDGXfzsVv/view},
year = {2009},
date = {2009-01-01},
booktitle = {XXXVI Ann. Conf. Computers in Cardiology},
pages = {681-684},
address = {Park City},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2007
Conferencias
Mincholé, A; Laguna, P
Discriminación entre isquemia de demanda y de suministro en registros Holter Conferencia
XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica, 2007.
@conference{Minchole_c107,
title = {Discriminación entre isquemia de demanda y de suministro en registros Holter},
author = {A Mincholé and P Laguna},
url = {https://drive.google.com/file/d/1-SPdhR8VzT1L5BOuMTjugL9g8awKFCeR/view},
year = {2007},
date = {2007-01-01},
booktitle = {XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica},
pages = {326-329},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Mincholé, A; Jager, F; Laguna, P
Discrimination between Demand and Supply Ischemia Episodes in Holter Recordings Conferencia
29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07), Lyon, 2007.
@conference{Minchole_c307,
title = {Discrimination between Demand and Supply Ischemia Episodes in Holter Recordings},
author = {A Mincholé and F Jager and P Laguna},
url = {https://drive.google.com/file/d/1rU1yTZex8q0fY6yfRsBz9-tiivYhfflJ/view},
year = {2007},
date = {2007-01-01},
booktitle = {29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07)},
pages = {2579-2582},
address = {Lyon},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2006
Conferencias
Mincholé, A; Martínez, J P; Arini, P; Risk, M; Laguna, P
Cambios en la repolarización cardiaca generados por la maniobra de Valsalva y medidos sobre el ECG Conferencia
XXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica, 2006.
@conference{Minchole_c106,
title = {Cambios en la repolarización cardiaca generados por la maniobra de Valsalva y medidos sobre el ECG},
author = {A Mincholé and J P Martínez and P Arini and M Risk and P Laguna},
url = {https://drive.google.com/file/d/1MG75q6NwFZVzyoOqKBzBcE7Na0yoNWou/view},
year = {2006},
date = {2006-01-01},
booktitle = {XXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica},
pages = {29-32},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Mincholé, A; Martínez, J P; Arini, P; Risk, M; Laguna, P
T Wave Width Alterations during Valsalva Maneuvers in Diabetic Patients Conferencia
Computers in Cardiology 2006, 2006.
@conference{Minchole_c206,
title = {T Wave Width Alterations during Valsalva Maneuvers in Diabetic Patients},
author = {A Mincholé and J P Martínez and P Arini and M Risk and P Laguna},
url = {https://drive.google.com/file/d/1auPnroj9S0ls-3DEcyJF9ymHjFw-kTvL/view},
year = {2006},
date = {2006-01-01},
booktitle = {Computers in Cardiology 2006},
pages = {709-712},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2005
Conferencias
Mincholé, A; Skarp, B; Jager, F; Laguna, P
XXIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, 2005.
@conference{Minchole_c205,
title = {Evaluación de un detector de isquemia basado en la raíz cuadrática media sobre la base de datos LTST con cancelación de cambios posturales},
author = {A Mincholé and B Skarp and F Jager and P Laguna},
url = {https://drive.google.com/file/d/1goB7HOOsoIpfHGd_AzlKRkNU71L9MYJO/view},
year = {2005},
date = {2005-01-01},
booktitle = {XXIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica},
pages = {121-124},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
Mincholé, A; Skarp, B; Laguna, P
XXXII Ann. Conf. Computers in Cardiology, Lyon, 2005.
@conference{Minchole_c105,
title = {Evaluation of a Root Mean Squared Based Ischemia Detector on the Long-Term ST Database with Body Position Change Cancellation},
author = {A Mincholé and B Skarp and P Laguna},
url = {https://drive.google.com/file/d/1gvlnZEun4AhlmHmHsiv9ToV29a3W0sz7/view},
year = {2005},
date = {2005-01-01},
booktitle = {XXXII Ann. Conf. Computers in Cardiology},
pages = {853-856},
address = {Lyon},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}