Projects ALL PROJECTS Identification of strong electrocardiographic and genetic predictors of sudden cardiac death risk aided by artificial intelligence (SUDDEN): CNS2023-143599Diabetic heart on chip for multiscale characterization of the ventricular remodeling in diabetic cardiomyopathy – DHOCTranslational cardioselective RNAi therapies and predictive heart-on-chip to tackle cardiac clinical challenges (ADVANCE) – PID2022-139859OB-I00Clinically-guided data processing methods and in silico models to improve patient stratification and therapy response in cardiac and neurological disorders: PID2022-140556OB-I00Multi-disciplinary, multi-sectoral and multi-national training network on digital biomarkers for supraventricular arrhythmia characterization and risk assessment. 101119941 (Call HORIZON-MSCA-2022-DN-01)CNS2022-135366: A neural interface based on peripheral recordings to measure and stimulate cortical rhythmsECHOES: Extracting the Human Motor Null Space from Muscles. A new framework to measure human neural activityDevelopment of accurate and physiologically meaningful digital twins of vascular hemodynamics using physics-informed neural networks (IMPULSO project)Closed-loop stimulation of the central nervous system to modulate tremoroscillations in the motor nervous system: PID-2022-138585OA-C32Customised DNA-based nanocarriers to boost heart healing (DNABEATS) – PCI 2023Implementation of wearable technology in primary health care for personalized exercise medicine (WearablePerMed) – PMP22/00002Major Depressive Disorder monitoring system: development of a platform based on wearable devices in relevant scenarios – PDC2022-133197-I00HEalthcare and MOnitoring DIgitalization in Chronic Illness management: application to multiple sclerosis and depression – TED2021-131106B-I00Monitoring and assessment of obstructive sleep apnea and its outcomes through the processing of physiological signals of wearables – PID2021-126734OB-C21Characterization of vital signs while drivingDigital transformation of clinical practice by using patient-specific cardiac digital twins for risk prediction and therapy optimization (DIGICARDIO) – TED2021-130459B-I00ECG morphology clusters for sudden cardiac death risk stratification in coronary artery disease using genetics and human-based computational models (STRATEGIC) – PID2021-128972OA-I00Advanced multifunction 3D biofabrication for the generation of computationally modelled human-scale therapeutic cardiac tissues – CARDIOPRINTClosed-loop corticospinal stimulation to suppress pathological tremors – LCF/BQ/PI21/11830018Consulting services for basic physiologic featuresComputational biomechanics and bioengineering 3D printing to develop a personalized regenerative biological ventricular assist devide to provide lasting functional support to damaged hearts – BRAV3 FinishedScientific Network Observatory for the Study and Prevention of Sudden Death in Sport (PREMUBID)PPG-based sleep apnea monitoringEquipment for the chronic electro-mechanical stimulation of cell and tissue cultures that allows their maintenance under biomimetic conditions. Force transducer and controller to program duration and amplitude of mechanical stretchFrom the brain to the heart: applications of dynamic systems analysis in biological modelsResearch Network in Epidemiology and Prevention of Cardiovascular Risk in SportsSpanish Research Network in Cardiac Computational ModelingTowards an early identification of depression through a process of physiological signals and metabolomic biomarkersFighting atrial fibrillation by acting on the signals that reach the heart from the nervous systemBiomarkers for Early Detection of Atrial Fibrillation Phase in Strenuous Exercise-Induced Atrial Cardiomyopathy: Prevention of Pafiyama SyndromePhysiologically guided signal analysis for ambulatory monitoring of depressionCharacterization and modeling of the physiological response in variable hyperbaric environmentsImproved monitoring of the autonomic nervous system during daily life applied to stress, depression and exerciseHuman cardiac ageing modeling and identification of age related electrophysiological markersCIBER-BBN: Centro de investigación biomédica en Red sobre Bioingeniería Biomateriales y NanomedicinaBiomedical monitoring prototype integrated in diving equipment for underwater environmentReference research group: Biomedical Signal Interpretation & Computational Simulation (BSICoS)Improvement of a device for real-time monitoring of the photoplestimographic signal in hyperbaric environmentsAutonomic nervous system surrogates, cardiopulmonary coupling and respiratory parameters as predictors of successful weaning in mechanically ventilated patientsPIC: Personalised in Silico CardiologyMY-ATRIA: MultidisciplinarY training network for ATrial fibRillation monItoring, treAtment and progressionDetection of K+ concentration alterations from the ECGValidation of pulse rate variability, respiratory frequency and stress assessment from NIVAbandWECARMON: Wearable Cardiorespiratory MonitorOptimization of a submersible device for monitoring the photoplesthymographic signalMulti-Scale Physiology-Driven Computational Tools To Assist In The Assessment And Management Of Cardiac Dysfunctions (MScPhCarDys)Biomedical Engineering and Medical Physics (BioMep)Remote Assessment of Disease and Relapse in Central Nervous System Disorders (RADAR-CNS)Multiscale computational tools to improve diagnosis, risk assessment and treatment in prevalent heart diseases (MULTITOOLS2HEART)Patterns of Autonomic Nervous System Biomarkers in Depression (DEANS)Multimodal analysis and m-Health tools for diagnostic and monitoring improving of Obstructive Lung Disease and Obstructive Sleep Apnea patients (M-LODOSA)Equipment for Dual Optical Mapping of Transmembrane Potential and Calcium TransientERC Starting Grant. Is your heart aging well? A systems biology approach to characterize cardiac aging from the cell to the body surface (MODELAGE)Effects of an early neurocognitive intervention on patient-ventilator interaction and stress in critically ill patients receiving mechanical ventilation (PVI-ANS-NCOG)Design and validation of a submersible device for the monitoring of the Autonomous Nervous System through the recording of pulse photoplethysmography in aquatic activitiesIdentification of situations of decreased performance of the military, based on the relationship of heart rate variability with stress and sleep deprivationStudy of the behavior of the autonomic nervous system and cognitive abilities in hyperbaric environmentsNoninvasive assessment of autonomic nervous system through the analysis of biosignals variability. Application to stress-related clinical problemDecision support systems in pathological or physiological stress by assessing the state of the autonomic nervous system through signal processingBiomedical Signal Interpretation and Computational Simulation (BSICoS). Grupo Consolidado de Investigación, reconocido por el Gobierno de AragónThe Autonomous Nervous System as a modulator of cardiac function: comprehensive investigation through signal processing and computational modelingPhysiology-guided signal processing for cardiac risk stratification and therapy-guided: tools to improve decision-making in cardiac managementComputer-assisted interpretation of electrical signals: a step forward in understanding and treating cardiac diseases (INTERCARDIO)QT-bed: Evaluation of changes in ventricular repolarization and its relationship with heart rate during bed-rest experimentsComputational investigation of cardiac arrhythmias and drug effect: from ion channels to the surface electrocardiogramMultimodal biomedical signal processing for the analysis and characterization of cardiovascular, respiratory and autonomic deseasesElectrocardiographic indices for myocardial ischemia diagnosis. Correlation between cellular mechanisms and manifestations on the surface electrical signal.Towards improved management of cardiovascular diseases by integrative in silico-in vitro-in vivo research into hearts structure, function and autonomic regulation – PID2019-105674RB-I00Physiology-driven signal analysis for guiding cardiac arrhythmia management and therapy – PID2019-104881RB-I00Physical activity for the prediction and prevention of cardiac risk: EXP_75053JIUZ2022-IAR-02: Respiration monitoring by means of a wrist-worn wearable device prototypeUZ2022-IAR-06: Towards a system for diagnosis and monitoring sleep apnea-hypopnea syndrome at home based on a wearable armbandStraight to the heart: development of cardio-selective microRNA nanotherapies (DIANA) – LMP128_21Efficacy, safety and mechanisms of new techniques for cardiac stimulation in patients with pacemakers: from computational research to clinical practice – LMP94_21Tidal Volume Monitoring by a Wearable ArmbandConfocal microscope with high performance Light Sheet based system and toxicity assessment platformReference research group: Biomedical Signal Interpretation & Computational Simulation (BSICoS)